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Objective <p>This study aims to explore the application of a multimodal prehabilitation strategy in patients undergoing laparoscopic sleeve gastrectomy (LSG) and to evaluate its impact on postoperative recovery, weight loss, and quality of life.</p> Methods <p>This was a single-center, prospective, randomized controlled trial. A total of 120 eligible patients undergoing elective LSG were enrolled and randomly assigned to either the control group (<i>n</i> = 60), receiving routine perioperative care, or the observation group (<i>n</i> = 60), receiving a structured 5–7-day prehabilitation program.</p> Results <p>Compared to the control group, the observation group had a significantly shorter postoperative hospital stay (mean difference [MD] −1.23&#xa0;days; 95% CI −1.67 to −0.79; <i>P </i>&lt; 0.001) and a lower incidence of complications (1.7% vs. 11.7%; odds ratio 0.13, 95% CI 0.02–0.89; <i>P</i> = 0.038). At 6&#xa0;months, the prehabilitation group showed a greater reduction in BMI (MD −3.78&#xa0;kg/m<sup>2</sup>; 95% CI −5.10 to −2.46; <i>P</i> &lt; 0.001) and higher quality of life scores across all eight SF-36 domains (<i>P</i> &lt; 0.001 for all).</p> Conclusion <p>The application of prehabilitation strategies in patients undergoing laparoscopic sleeve gastrectomy can effectively promote faster postoperative recovery, enhance weight loss, improve quality of life, and reduce the incidence of postoperative complications. It is a safe and effective approach, worthy of clinical promotion. Furthermore, the principles of this multimodal prehabilitation framework offer valuable translational insights for optimizing perioperative supportive care in surgical oncology.</p>

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Effectiveness of prehabilitation strategies in enhancing recovery and postoperative outcomes in laparoscopic sleeve gastrectomy patients

  • 期刊论文

  • 发表日期：

    2026年4月10日

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  • Guihua Zhang,
  • Miaomiao Zhang,
  • Cuina Zhang,
  • Na Li,
  • Jian Zhang,
  • Yan Zhang,
  • Yankai Zhao

摘要

Objective

This study aims to explore the application of a multimodal prehabilitation strategy in patients undergoing laparoscopic sleeve gastrectomy (LSG) and to evaluate its impact on postoperative recovery, weight loss, and quality of life.

Methods

This was a single-center, prospective, randomized controlled trial. A total of 120 eligible patients undergoing elective LSG were enrolled and randomly assigned to either the control group (n = 60), receiving routine perioperative care, or the observation group (n = 60), receiving a structured 5–7-day prehabilitation program.

Results

Compared to the control group, the observation group had a significantly shorter postoperative hospital stay (mean difference [MD] −1.23 days; 95% CI −1.67 to −0.79; P < 0.001) and a lower incidence of complications (1.7% vs. 11.7%; odds ratio 0.13, 95% CI 0.02–0.89; P = 0.038). At 6 months, the prehabilitation group showed a greater reduction in BMI (MD −3.78 kg/m2; 95% CI −5.10 to −2.46; P < 0.001) and higher quality of life scores across all eight SF-36 domains (P < 0.001 for all).

Conclusion

The application of prehabilitation strategies in patients undergoing laparoscopic sleeve gastrectomy can effectively promote faster postoperative recovery, enhance weight loss, improve quality of life, and reduce the incidence of postoperative complications. It is a safe and effective approach, worthy of clinical promotion. Furthermore, the principles of this multimodal prehabilitation framework offer valuable translational insights for optimizing perioperative supportive care in surgical oncology.