Objective <p>Investigation of the Prevalence of Cognitive Impairment and Its Influencing Factors in Patients with Different Cancer Types.</p> Methods <p>A convenience sample of 1,269 cancer patients who were diagnosed and treated at our hospital from May 2024 to December 2024 was enrolled in the study. Assessments included the General Information Questionnaire, the Montreal Cognitive Assessment (MoCA), the Cancer Fatigue Scale (CFS), the Hospital Anxiety and Depression Scale (HADS), the Athens Insomnia Scale (AIS), and the Visual Analog Scale (VAS). Binary logistic regression analysis was used to identify factors influencing cognitive impairment among patients with different cancer types.</p> Results <p>The average MoCA score for the 1,269 cancer patients was 22.71 ± 5.23, and 65.40% of the patients exhibited cognitive impairment. The binary logistic regression analysis indicated that clinical diagnosis, pain intensity, and the presence of depression were significant factors influencing Cognitive impairment (<i>P</i> &lt; 0.05).</p> Conclusion <p>Cognitive impairment is highly prevalent in cancer patients, with significant variations observed across different cancer types. Pain and depression are key factors associated with this condition. The findings of this study suggest that in clinical care, routine cognitive screening should be conducted for patients with moderate to severe pain or depressive symptoms to facilitate the early identification of high-risk populations, thereby providing an evidence-based foundation for the delivery of targeted interventions and the improvement of patients’ quality of life in the future.</p>

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Analysis of the current status and influencing factors of cognitive impairment in patients with different cancer types: a cross-sectional study

  • Chen Hu,
  • Yanfang Zheng,
  • Xin Wang,
  • Jie Li,
  • Hao Gong,
  • Ziqi Zhang,
  • Shuyan Xing,
  • Jiyu Wang,
  • Yang Yang,
  • Huiyi Lv

摘要

Objective

Investigation of the Prevalence of Cognitive Impairment and Its Influencing Factors in Patients with Different Cancer Types.

Methods

A convenience sample of 1,269 cancer patients who were diagnosed and treated at our hospital from May 2024 to December 2024 was enrolled in the study. Assessments included the General Information Questionnaire, the Montreal Cognitive Assessment (MoCA), the Cancer Fatigue Scale (CFS), the Hospital Anxiety and Depression Scale (HADS), the Athens Insomnia Scale (AIS), and the Visual Analog Scale (VAS). Binary logistic regression analysis was used to identify factors influencing cognitive impairment among patients with different cancer types.

Results

The average MoCA score for the 1,269 cancer patients was 22.71 ± 5.23, and 65.40% of the patients exhibited cognitive impairment. The binary logistic regression analysis indicated that clinical diagnosis, pain intensity, and the presence of depression were significant factors influencing Cognitive impairment (P < 0.05).

Conclusion

Cognitive impairment is highly prevalent in cancer patients, with significant variations observed across different cancer types. Pain and depression are key factors associated with this condition. The findings of this study suggest that in clinical care, routine cognitive screening should be conducted for patients with moderate to severe pain or depressive symptoms to facilitate the early identification of high-risk populations, thereby providing an evidence-based foundation for the delivery of targeted interventions and the improvement of patients’ quality of life in the future.