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Purpose <p>At the National Hospital Organization Kumamoto Medical Center, the supportive care team (SCT) provides supportive care to all patients with head and neck cancer (HNC) undergoing concurrent chemoradiotherapy (CCRT). This study aimed to investigate the relationship between SCT intervention and the nutritional status, adverse events, and treatment status of patients with HNC undergoing CCRT.</p> Methods <p>This study enrolled 40 patients with HNC who underwent CCRT. The primary endpoint was the body weight (BW) loss rate. The secondary endpoints were energy intake, incidence of adverse events, and treatment completion rate.</p> Results <p>BW loss rate (9.0 ± 5.0 <i>vs.</i> 5.5 ± 3.4%; <i>p</i> = 0.017) was significantly lower in the SCT intervention group (<i>n</i> = 20) than in the non-SCT intervention group (<i>n</i> = 20). The energy intake of radiation therapy (RT) 22–40 Gy (21.0 ± 6.9 <i>vs.</i> 25.4 ± 4.6 kcal/kg ideal BW [IBW]; <i>p</i> = 0.024) and RT 42–60 Gy (22.6 ± 7.2 <i>vs.</i> 26.3 ± 3.8 kcal/kg IBW; <i>p</i> = 0.048) were significantly higher in the SCT intervention group than in the non-SCT intervention group. The incidence of grade 3 or higher oral mucositis was significantly lower in the SCT intervention group than in the non-SCT intervention group (40.0 <i>vs.</i> 10.0%; <i>p</i> = 0.028). The completion rate of CCRT was significantly higher in the SCT intervention group than in the non-SCT intervention group (55.0 <i>vs.</i> 85.0%; <i>p</i> = 0.038).</p> Conclusion <p>SCT intervention in patients with HNC undergoing CCRT was associated with reduced BW loss rate.</p>

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Association of supportive care team intervention with nutritional status, adverse events, and treatment status in patients with head and neck cancer undergoing concurrent chemoradiotherapy

  • 期刊论文

  • 发表日期：

    2025年10月14日

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  • Akiho Yamashita,
  • Masayuki Kaku,
  • Misato Otsuka,
  • Eriko Matsumoto,
  • Kayo Nakao,
  • Satomi Inoue,
  • Yuki Terada,
  • Mifumi Nakao,
  • Etsushi Tomitaka,
  • Naoki Uemura,
  • Tatsunori Sakai

摘要

Purpose

At the National Hospital Organization Kumamoto Medical Center, the supportive care team (SCT) provides supportive care to all patients with head and neck cancer (HNC) undergoing concurrent chemoradiotherapy (CCRT). This study aimed to investigate the relationship between SCT intervention and the nutritional status, adverse events, and treatment status of patients with HNC undergoing CCRT.

Methods

This study enrolled 40 patients with HNC who underwent CCRT. The primary endpoint was the body weight (BW) loss rate. The secondary endpoints were energy intake, incidence of adverse events, and treatment completion rate.

Results

BW loss rate (9.0 ± 5.0 vs. 5.5 ± 3.4%; p = 0.017) was significantly lower in the SCT intervention group (n = 20) than in the non-SCT intervention group (n = 20). The energy intake of radiation therapy (RT) 22–40 Gy (21.0 ± 6.9 vs. 25.4 ± 4.6 kcal/kg ideal BW [IBW]; p = 0.024) and RT 42–60 Gy (22.6 ± 7.2 vs. 26.3 ± 3.8 kcal/kg IBW; p = 0.048) were significantly higher in the SCT intervention group than in the non-SCT intervention group. The incidence of grade 3 or higher oral mucositis was significantly lower in the SCT intervention group than in the non-SCT intervention group (40.0 vs. 10.0%; p = 0.028). The completion rate of CCRT was significantly higher in the SCT intervention group than in the non-SCT intervention group (55.0 vs. 85.0%; p = 0.038).

Conclusion

SCT intervention in patients with HNC undergoing CCRT was associated with reduced BW loss rate.