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Purpose <p>Self-care during radiotherapy (RT) is crucial for managing mucositis and dermatitis in patients with head and neck squamous cell carcinomas (HNSCC). However, elderly patients often struggle with self-care. This study examined the relationship between self-care decline and the Geriatric 8 (G8) score.</p> Methods <p>A retrospective analysis was conducted on 66 patients (≥ 65 years) with HNSCC who met the inclusion and exclusion criteria and received definitive RT between December 2018 and February 2023. Self-care activities—medication adherence, oral care, grooming, skin ointment application, and gauze dressing—were assessed during definitive RT on a 0–5 scale. Patients were first grouped by initial self-care independence, and their G8 scores were compared. Among initially independent patients, those with self-care score changes were further analyzed based on their G8 scores. A threshold value was also determined to differentiate between the groups.</p> Results <p>The initially independent group exhibited significantly higher G8 scores than non-independent group (median G8 score: 14 vs. 9.75, <i>P</i> = 0.0067). Among the initially independent patients, 15 (24.2%) experienced self-care decline, and lower baseline G8 scores significantly predicted this deterioration (median　G8 score: 12 vs. 15; <i>P</i> = 0.011). Multivariate analysis identified G8 scores as a significant predictor of self-care decline (odds ratio = 6.53, <i>P</i> = 0.0074). Receiver operating characteristic (ROC) analysis determined a G8 cutoff of 12 (area under the curve = 0.72) with 53.3% sensitivity and 85.1% specificity.</p> Conclusion <p>These findings indicate a possible coherence between the absence of frailty and maintenance of self-care in elderly patients undergoing RT. Further, prospectively designed research is needed to confirm these findings in a larger cohort.</p>

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Association between geriatric 8 (G8) scores and self-care decline in elderly patients with head and neck squamous cell carcinoma undergoing radiotherapy

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年9月16日

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  • Tsuyoshi Katsuta,
  • Ikuno Nishibuchi,
  • Miki Fujioka,
  • Megumi Nomura,
  • Miho Kondo,
  • Takao Hamamoto,
  • Tsutomu Ueda,
  • Hiroki Ochi,
  • Hiroshi Sakauchi,
  • Shigeyuki Tani,
  • Nobuki Imano,
  • Yuji Murakami

摘要

Purpose

Self-care during radiotherapy (RT) is crucial for managing mucositis and dermatitis in patients with head and neck squamous cell carcinomas (HNSCC). However, elderly patients often struggle with self-care. This study examined the relationship between self-care decline and the Geriatric 8 (G8) score.

Methods

A retrospective analysis was conducted on 66 patients (≥ 65 years) with HNSCC who met the inclusion and exclusion criteria and received definitive RT between December 2018 and February 2023. Self-care activities—medication adherence, oral care, grooming, skin ointment application, and gauze dressing—were assessed during definitive RT on a 0–5 scale. Patients were first grouped by initial self-care independence, and their G8 scores were compared. Among initially independent patients, those with self-care score changes were further analyzed based on their G8 scores. A threshold value was also determined to differentiate between the groups.

Results

The initially independent group exhibited significantly higher G8 scores than non-independent group (median G8 score: 14 vs. 9.75, P = 0.0067). Among the initially independent patients, 15 (24.2%) experienced self-care decline, and lower baseline G8 scores significantly predicted this deterioration (median　G8 score: 12 vs. 15; P = 0.011). Multivariate analysis identified G8 scores as a significant predictor of self-care decline (odds ratio = 6.53, P = 0.0074). Receiver operating characteristic (ROC) analysis determined a G8 cutoff of 12 (area under the curve = 0.72) with 53.3% sensitivity and 85.1% specificity.

Conclusion

These findings indicate a possible coherence between the absence of frailty and maintenance of self-care in elderly patients undergoing RT. Further, prospectively designed research is needed to confirm these findings in a larger cohort.