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Objectives <p>This longitudinal study aimed to examine the relationship between return-to-work self-efficacy (RTW-SE), anxiety, and depression in patients with renal cancer.</p> Methods <p>A total of 282 patients with renal cancer from Sun Yat-sen University Cancer Center were recruited between April and December 2022. Patients were assessed at one month (T1), three months (T2), and six months (T3) after surgery using a general information questionnaire, Return-to-Work Self-Efficacy Scale, Generalized Anxiety Disorder Scale (GAD- 7), and Patient Health Questionnaire (PHQ- 9).</p> Results <p>RTW-SE progressively increased over time, while anxiety and depression scores showed a decreasing trend. Pearson’s correlation analysis revealed a significant negative association between RTW-SE and both anxiety and depression at all three-time points. Cross-lagged analysis demonstrated that RTW-SE at T1 significantly predicted depression at T2 (<i>β</i> = - 0.066, <i>P</i> &lt; 0.001), whereas RTW-SE at T2 significantly predicted both anxiety (<i>β</i> = - 0.177, <i>P</i> &lt; 0.001) and depression (<i>β</i> = - 0.077, <i>P</i> &lt; 0.001) at T3.</p> Conclusion <p>Higher RTW-SE scores were associated with lower levels of post-surgery anxiety and depression. These findings highlight the importance of systematic RTW-SE assessments and early interventions to enhance work reintegration and psychological well-being. Incorporating RTW-SE monitoring into postoperative care plans may help to identify high-risk patients and facilitate timely psychological and vocational support.</p>

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The relationship between returning to work self-efficacy, anxiety, and depression in renal cancer patients: a cross-lagged analysis

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年4月10日

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  • Xiaoping Chen,
  • Man Xu,
  • Guolong Chen,
  • Huiming Lu,
  • Huiting Zhang,
  • Mengxiao Jiang

摘要

Objectives

This longitudinal study aimed to examine the relationship between return-to-work self-efficacy (RTW-SE), anxiety, and depression in patients with renal cancer.

Methods

A total of 282 patients with renal cancer from Sun Yat-sen University Cancer Center were recruited between April and December 2022. Patients were assessed at one month (T1), three months (T2), and six months (T3) after surgery using a general information questionnaire, Return-to-Work Self-Efficacy Scale, Generalized Anxiety Disorder Scale (GAD- 7), and Patient Health Questionnaire (PHQ- 9).

Results

RTW-SE progressively increased over time, while anxiety and depression scores showed a decreasing trend. Pearson’s correlation analysis revealed a significant negative association between RTW-SE and both anxiety and depression at all three-time points. Cross-lagged analysis demonstrated that RTW-SE at T1 significantly predicted depression at T2 (β = - 0.066, P < 0.001), whereas RTW-SE at T2 significantly predicted both anxiety (β = - 0.177, P < 0.001) and depression (β = - 0.077, P < 0.001) at T3.

Conclusion

Higher RTW-SE scores were associated with lower levels of post-surgery anxiety and depression. These findings highlight the importance of systematic RTW-SE assessments and early interventions to enhance work reintegration and psychological well-being. Incorporating RTW-SE monitoring into postoperative care plans may help to identify high-risk patients and facilitate timely psychological and vocational support.