Scholarlink

<p>Acute metabolic crises can be potentially life-threatening situations in adults depending on the extent. Therefore, rapid comprehensive diagnostic and therapeutic measures with close monitoring of vital and laboratory parameters are required. The treatment of diabetic ketoacidosis (DKA) and the hyperosmolar hyperglycemic state (HHS) is essentially the same and replacement of the mostly substantial fluid deficit with several liters of a&#xa0;physiological crystalloid solution is the first and most important step. Serum potassium concentrations need to be carefully monitored to guide its substitution. Regular insulin or rapid-acting insulin analogues can be initially administered as an i.v. bolus followed by continuous infusion. Insulin should be switched to subcutaneous injections only after correction of the acidosis and stable glucose concentrations within an acceptable range.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Therapie der akuten diabetischen Stoffwechselentgleisungen bei Erwachsenen (Update 2026)

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年4月30日

查看全文
  • Michael Resl,
  • Susanne Kaser,
  • Harald Sourij,
  • Martin Clodi,
  • Bruno Schneeweiß,
  • Anton Luger

摘要

Acute metabolic crises can be potentially life-threatening situations in adults depending on the extent. Therefore, rapid comprehensive diagnostic and therapeutic measures with close monitoring of vital and laboratory parameters are required. The treatment of diabetic ketoacidosis (DKA) and the hyperosmolar hyperglycemic state (HHS) is essentially the same and replacement of the mostly substantial fluid deficit with several liters of a physiological crystalloid solution is the first and most important step. Serum potassium concentrations need to be carefully monitored to guide its substitution. Regular insulin or rapid-acting insulin analogues can be initially administered as an i.v. bolus followed by continuous infusion. Insulin should be switched to subcutaneous injections only after correction of the acidosis and stable glucose concentrations within an acceptable range.