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<p>The present case report describes a&#xa0;completely ulcerated infantile hemangioma (UIH) in a&#xa0;5-month-old infant on the left proximolateral thigh initially misdiagnosed as pyoderma gangrenosum, sporotrichosis or atypical mycobacterial infection. Clinical assessment, histological findings, and GLUT‑1 immunohistochemistry confirmed the diagnosis of UIH. Systemic propranolol treatment led to rapid ulcer healing within 3&#xa0;weeks and complete recovery without relapse after 18&#xa0;months of treatment. The report emphasizes the diagnostic challenges, effective propranolol treatment and the importance of considering UIH in the differential diagnoses of solitary pediatric ulcers.</p>

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Completely ulcerated infantile hemangioma: a diagnostic challenge

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年5月22日

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  • Elias Marquart,
  • Doris Weiss,
  • Klaudija Batinic,
  • Thomas Wiesner,
  • Johannes Rohrbeck,
  • Tamara Arnoldner,
  • Wolfgang Weninger,
  • Tamar Kinaciyan

摘要

The present case report describes a completely ulcerated infantile hemangioma (UIH) in a 5-month-old infant on the left proximolateral thigh initially misdiagnosed as pyoderma gangrenosum, sporotrichosis or atypical mycobacterial infection. Clinical assessment, histological findings, and GLUT‑1 immunohistochemistry confirmed the diagnosis of UIH. Systemic propranolol treatment led to rapid ulcer healing within 3 weeks and complete recovery without relapse after 18 months of treatment. The report emphasizes the diagnostic challenges, effective propranolol treatment and the importance of considering UIH in the differential diagnoses of solitary pediatric ulcers.