Scholarlink

<p>A 16-year-old male presented with seizure to an outside hospital and was found to have severe kidney dysfunction of unknown chronicity. He had dilute urine throughout the hospitalization and a negative serological work-up for acute glomerulonephritis. Exposure history was notable for 1–2 doses of ibuprofen and ondansetron use for nausea for the 3–4 days prior to the admission. All prior medications were discontinued, and he was started on levetiracetam for seizure management. Kidney function markedly improved on hospital day 4, and a planned kidney biopsy was cancelled. Kidney function continued to normalize after discharge. He experienced nausea again 10 days after discharge and took another dose of ondansetron with increased creatinine noted 1 day later. After discontinuation of ondansetron, his kidney function returned to and has remained normal.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Acute interstitial nephritis associated with ondansetron

  • 期刊论文

  • 发表日期：

    2025年6月2日

查看全文
  • Olga Charnaya,
  • Elizabeth Goswami

摘要

A 16-year-old male presented with seizure to an outside hospital and was found to have severe kidney dysfunction of unknown chronicity. He had dilute urine throughout the hospitalization and a negative serological work-up for acute glomerulonephritis. Exposure history was notable for 1–2 doses of ibuprofen and ondansetron use for nausea for the 3–4 days prior to the admission. All prior medications were discontinued, and he was started on levetiracetam for seizure management. Kidney function markedly improved on hospital day 4, and a planned kidney biopsy was cancelled. Kidney function continued to normalize after discharge. He experienced nausea again 10 days after discharge and took another dose of ondansetron with increased creatinine noted 1 day later. After discontinuation of ondansetron, his kidney function returned to and has remained normal.