<p>Metal components operating in high-temperature environments are prone to creep damage due to the combined effects of continuous constant stress and thermal loading, which may ultimately lead to structural failure. Conventional creep life prediction models, such as the Larson–Miller parameter and θ‑projection method, are largely empirical, ignoring energy dissipation and micro‑damage mechanisms, which makes them inherently limited for accurate creep failure prediction. To overcome the above limitations, this work develops two models which take thermodynamics as the theoretical basis and regard entropy generation as the core characterization indicator. Specifically, the first‑type model couples energy dissipation with temperature to quantify entropy generation from irreversible processes. The second‑type model uses creep strain as the dominant variable, links macroscopic stress to mesoscopic plastic deformation, and the thermodynamic state index (TSI) is introduced as a failure criterion. Finally, the proposed method is validated using material strain data obtained from high-temperature creep experiments. The results reveal that both models exhibit good predictive performance, and the second-type model achieves better accuracy under high-temperature conditions.</p>