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Background <p>Recurrent weight gain (RWG) after Roux-en-Y gastric bypass (RYGB) is an increasingly common challenge. Biliopancreatic diversion with duodenal switch (BPD/DS) and single anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S) are surgical options available for achieving optimal clinical response in these patients.</p> Objectives <p>This study aimed to compare the characteristics and outcomes of patients who underwent either BPD/DS or SADI-S following RYGB.</p> Methods <p>An analysis of the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP) database was conducted, focusing on patients from 2020 to 2022 who underwent BPD/DS or SADI-S following a primary RYGB. Postoperative bariatric outcomes, complication rates, and weight loss metrics—including percentage of excess weight loss (%EWL), total weight loss (%TWL), and excess BMI loss (%EBMIL) at 30&#xa0;days—were evaluated. A stratified analysis was also performed to assess differences between the procedures.</p> Results <p>A total of 616 patients were included. 75.5% (<i>n</i> = 465) underwent BPD/DS and 24.5% (<i>n</i> = 151) SADI after RYGB. The majority of patients were female (90.7%, <i>n</i> = 559), with a mean age of 48.2 ± 9.1&#xa0;years. The mean preoperative body mass index (BMI) was 47.5 ± 8.3 for patients undergoing BPD/DS and 44.5 ± 6.8 for those undergoing SADI (<i>p</i> &lt; 0.001). Patients who underwent BPD/DS had a higher prevalence of hypertension (47% vs. 33.7%, <i>p</i> = 0.004) and ASA IV classification (12.2% vs. 1.3%, <i>p</i> &lt; 0.001), but a lower rate of drain placement compared to those who underwent SADI (31.8% vs. 45%, <i>p</i> = 0.003). There was no statistically significant difference in terms of length of stay, operative time, or intraoperative/postoperative complications in the first 30&#xa0;days. Weight loss outcomes at 30&#xa0;days were comparable between the BPD/DS and SADI approaches.</p> Conclusions <p>Among patients undergoing conversion after RYGB, BPD/DS and SADI demonstrated comparable short-term bariatric outcomes, with similar 30-day postoperative complication rates.</p>

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Safety and feasibility of conversion of Roux-en-Y gastric bypass to BPD/DS versus SADI: an analysis of MBSAQIP database

  • 期刊论文

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  • 发表日期：

    2026年1月22日

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  • J. L. Serra,
  • A. Estrada,
  • Y. Rivero-Moreno,
  • N. Hindosh,
  • J. Choi,
  • E. Moran-Atkin,
  • D. Camacho

摘要

Background

Recurrent weight gain (RWG) after Roux-en-Y gastric bypass (RYGB) is an increasingly common challenge. Biliopancreatic diversion with duodenal switch (BPD/DS) and single anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S) are surgical options available for achieving optimal clinical response in these patients.

Objectives

This study aimed to compare the characteristics and outcomes of patients who underwent either BPD/DS or SADI-S following RYGB.

Methods

An analysis of the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP) database was conducted, focusing on patients from 2020 to 2022 who underwent BPD/DS or SADI-S following a primary RYGB. Postoperative bariatric outcomes, complication rates, and weight loss metrics—including percentage of excess weight loss (%EWL), total weight loss (%TWL), and excess BMI loss (%EBMIL) at 30 days—were evaluated. A stratified analysis was also performed to assess differences between the procedures.

Results

A total of 616 patients were included. 75.5% (n = 465) underwent BPD/DS and 24.5% (n = 151) SADI after RYGB. The majority of patients were female (90.7%, n = 559), with a mean age of 48.2 ± 9.1 years. The mean preoperative body mass index (BMI) was 47.5 ± 8.3 for patients undergoing BPD/DS and 44.5 ± 6.8 for those undergoing SADI (p < 0.001). Patients who underwent BPD/DS had a higher prevalence of hypertension (47% vs. 33.7%, p = 0.004) and ASA IV classification (12.2% vs. 1.3%, p < 0.001), but a lower rate of drain placement compared to those who underwent SADI (31.8% vs. 45%, p = 0.003). There was no statistically significant difference in terms of length of stay, operative time, or intraoperative/postoperative complications in the first 30 days. Weight loss outcomes at 30 days were comparable between the BPD/DS and SADI approaches.

Conclusions

Among patients undergoing conversion after RYGB, BPD/DS and SADI demonstrated comparable short-term bariatric outcomes, with similar 30-day postoperative complication rates.