Scholarlink

Introduction <p>Venous thromboembolism (VTE) events, such as pulmonary embolism (PE) and deep venous thrombosis (DVT), are a significant source of morbidity and mortality after major abdominal wall reconstruction. We aim to describe the incidence of VTE events in patients undergoing ventral hernia repair (VHR) with transversus abdominis release (TAR) at our institution.</p> Methods <p>The Abdominal Core Health Quality Collaborative registry was queried for patients, 18&#xa0;years and older, who underwent VHR with TAR at our institution between August 2014 and December 2023. Patient characteristics and operative details were obtained from the registry. Patient electronic medical records were reviewed for outcomes. The primary study outcome was the incidence of VTE, including PE and DVT, within 8&#xa0;weeks postoperatively. Secondary outcomes included time to VTE, VTE chemoprophylaxis protocol used, VTE management, and complications.</p> Results <p>Of the 3555 patients who underwent abdominal wall reconstruction and met inclusion criteria, 100 patients experienced (2.8%) VTE events; 58 patients had a PE and 42 had DVTs. The median time to a VTE event was 7 (IQR 4–14) days after surgery, and 27% of VTE events occurred after hospital discharge. Of the patients who experienced a VTE event, 77 received preoperative chemoprophylaxis and 66 patients received postoperative chemoprophylaxis beginning on the day of surgery. In 19 patients, chemoprophylaxis was interrupted prior to development of VTE. Most patients (<i>n</i> = 88) were managed with systemic anticoagulation, and 18.1% had a bleeding complication related to anticoagulation treatment.</p> Conclusion <p>Patients undergoing major abdominal wall reconstruction are at high risk for venous thromboembolism events, even after hospital discharge. Further studies are needed to determine risk factors associated with VTE in this specific patient population to optimize perioperative anticoagulation strategies.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Venous thromboembolism after ventral hernia repair with transversus abdominis release

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年7月30日

查看全文
  • Kimberly P. Woo,
  • Sergio Mazzola Poli de Figueiredo,
  • Sarah L. Larson,
  • Joseph D. Quick,
  • Sara M. Maskal,
  • Daphne Remulla,
  • William C. Bennett,
  • Kimberly S. Miles,
  • Chao Tu,
  • Lucas R. Beffa,
  • Clayton C. Petro,
  • Ajita S. Prabhu,
  • David M. Krpata,
  • Michael J. Rosen,
  • Benjamin T. Miller

摘要

Introduction

Venous thromboembolism (VTE) events, such as pulmonary embolism (PE) and deep venous thrombosis (DVT), are a significant source of morbidity and mortality after major abdominal wall reconstruction. We aim to describe the incidence of VTE events in patients undergoing ventral hernia repair (VHR) with transversus abdominis release (TAR) at our institution.

Methods

The Abdominal Core Health Quality Collaborative registry was queried for patients, 18 years and older, who underwent VHR with TAR at our institution between August 2014 and December 2023. Patient characteristics and operative details were obtained from the registry. Patient electronic medical records were reviewed for outcomes. The primary study outcome was the incidence of VTE, including PE and DVT, within 8 weeks postoperatively. Secondary outcomes included time to VTE, VTE chemoprophylaxis protocol used, VTE management, and complications.

Results

Of the 3555 patients who underwent abdominal wall reconstruction and met inclusion criteria, 100 patients experienced (2.8%) VTE events; 58 patients had a PE and 42 had DVTs. The median time to a VTE event was 7 (IQR 4–14) days after surgery, and 27% of VTE events occurred after hospital discharge. Of the patients who experienced a VTE event, 77 received preoperative chemoprophylaxis and 66 patients received postoperative chemoprophylaxis beginning on the day of surgery. In 19 patients, chemoprophylaxis was interrupted prior to development of VTE. Most patients (n = 88) were managed with systemic anticoagulation, and 18.1% had a bleeding complication related to anticoagulation treatment.

Conclusion

Patients undergoing major abdominal wall reconstruction are at high risk for venous thromboembolism events, even after hospital discharge. Further studies are needed to determine risk factors associated with VTE in this specific patient population to optimize perioperative anticoagulation strategies.