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Purpose <p>This study investigated the influence of nutritional status on patient-reported outcomes after surgical treatment for chronic venous disease (CVD). It aimed to compare improvements in symptom severity (VEINES-Sym) and quality of life (VEINES-QOL) between endovenous laser ablation (EVLA) and combined crossectomy, stripping, and sclerotherapy (CEEE), with analysis stratified by nutritional status.</p> Methods <p>In a prospective cohort study of 157 patients (95 CEEE, 62 EVLA), nutritional status was categorized by body mass index as eutrophic, overweight, or obese. VEINES-Sym and VEINES-QOL scores were collected preoperatively and 30–60 days postoperatively. Statistical analysis used paired t-tests for within-group comparisons, the Kruskal-Wallis test across nutritional strata, and independent t-tests to compare surgical techniques.</p> Results <p>Both techniques produced significant improvements (<i>p</i> &lt; 0.05) in VEINES-Sym and VEINES-QOL scores across all nutritional categories. Preoperatively, patients with obesity had significantly worse baseline scores. Postoperatively, these differences were no longer significant (<i>p</i> &gt; 0.05), with all groups achieving comparable scores. The magnitude of symptom improvement was similar for both techniques. However, postoperative VEINES-QOL scores were significantly higher in the EVLA group (94.7 ± 9.9) than in the CEEE group (90.5 ± 13.7; <i>p</i> = 0.015).</p> Conclusion <p>Although poorer nutritional status is associated with greater preoperative symptom severity, it does not diminish the significant clinical benefit of surgical intervention. Both CEEE and EVLA effectively improve symptoms and quality of life, enabling all patient groups to attain similar postoperative outcomes.</p>

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Influence of nutritional status on patient-reported outcomes after surgical treatment for chronic venous disease: a comparative study between endovenous laser ablation and combined crossectomy, stripping, and sclerotherapy

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年4月18日

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  • Vinicius Nicolao Capacia,
  • Raquel Bragança Soares Capacia,
  • Ana Paula Ribeiro,
  • Elias Jirjoss Ilias,
  • Patrícia Colombo-Souza

摘要

Purpose

This study investigated the influence of nutritional status on patient-reported outcomes after surgical treatment for chronic venous disease (CVD). It aimed to compare improvements in symptom severity (VEINES-Sym) and quality of life (VEINES-QOL) between endovenous laser ablation (EVLA) and combined crossectomy, stripping, and sclerotherapy (CEEE), with analysis stratified by nutritional status.

Methods

In a prospective cohort study of 157 patients (95 CEEE, 62 EVLA), nutritional status was categorized by body mass index as eutrophic, overweight, or obese. VEINES-Sym and VEINES-QOL scores were collected preoperatively and 30–60 days postoperatively. Statistical analysis used paired t-tests for within-group comparisons, the Kruskal-Wallis test across nutritional strata, and independent t-tests to compare surgical techniques.

Results

Both techniques produced significant improvements (p < 0.05) in VEINES-Sym and VEINES-QOL scores across all nutritional categories. Preoperatively, patients with obesity had significantly worse baseline scores. Postoperatively, these differences were no longer significant (p > 0.05), with all groups achieving comparable scores. The magnitude of symptom improvement was similar for both techniques. However, postoperative VEINES-QOL scores were significantly higher in the EVLA group (94.7 ± 9.9) than in the CEEE group (90.5 ± 13.7; p = 0.015).

Conclusion

Although poorer nutritional status is associated with greater preoperative symptom severity, it does not diminish the significant clinical benefit of surgical intervention. Both CEEE and EVLA effectively improve symptoms and quality of life, enabling all patient groups to attain similar postoperative outcomes.