Scholarlink

Purpose <p>This study aims to evaluate and compare intraocular pressure (IOP) change and topical IOP-lowering medication use after combined cataract surgery with iStent <i>inject</i><sup>®</sup> W implantation versus cataract surgery alone in patients with open-angle glaucoma.</p> Methods <p>Retrospective comparative chart review of 150 patients (150 eyes) with different types of open-angle glaucoma, who were naïve to any previous ocular procedure and underwent combined cataract surgery with iStent<sup>®</sup> W implantation (100 eyes) or cataract surgery alone (50 eyes). Study outcomes were median IOP change and the mean number of topical IOP-lowering medications at 3, 6 and 12 months after surgery.</p> Results <p>The median IOP change in the iStent inject<sup>®</sup> W group at 3-, 6- and 12 months follow-up was − 4 (-6 to -2) mmHg (<i>p</i> &lt; 0.001), -4 (-6 to -1) mmHg (<i>p</i> &lt; 0.001), and − 4 (-6.75 to -2) mmHg (<i>p</i> &lt; 0.001), respectively. The median IOP change in the control group at 3-, 6- and 12 months follow-up was 0 (-1.25 to 2) mmHg, 1 (-1 to 3) mmHg, and 0 (-2.5 to 3) mmHg, respectively. IOP reduction in the study group was statistically significantly larger than in the control group at all follow-ups (<i>p</i> &lt; 0.001). We found a statistically significant difference between the mean number of topical IOP-lowering medications before and at 12 months in the combined surgery group (<i>p</i> &lt; 0.001) as compared to the control group.</p> Conclusions <p>This study shows a statistically significant IOP reduction at 3-, 6- and 12 months and reduction of topical IOP-lowering medications at 12 months after combined cataract surgery with iStent <i>inject</i><sup>®</sup> W implantation.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Clinical outcomes of combined cataract surgery with iStent inject® W implantation versus cataract surgery alone in patients with open-angle glaucoma: real life data in a community-based outpatient setting

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年8月27日

查看全文
  • Fidan A. Aghayeva,
  • Abdelrahman Assaf,
  • Shakriiar Gurbanzade,
  • Ines M. Lanzl

摘要

Purpose

This study aims to evaluate and compare intraocular pressure (IOP) change and topical IOP-lowering medication use after combined cataract surgery with iStent inject® W implantation versus cataract surgery alone in patients with open-angle glaucoma.

Methods

Retrospective comparative chart review of 150 patients (150 eyes) with different types of open-angle glaucoma, who were naïve to any previous ocular procedure and underwent combined cataract surgery with iStent® W implantation (100 eyes) or cataract surgery alone (50 eyes). Study outcomes were median IOP change and the mean number of topical IOP-lowering medications at 3, 6 and 12 months after surgery.

Results

The median IOP change in the iStent inject® W group at 3-, 6- and 12 months follow-up was − 4 (-6 to -2) mmHg (p < 0.001), -4 (-6 to -1) mmHg (p < 0.001), and − 4 (-6.75 to -2) mmHg (p < 0.001), respectively. The median IOP change in the control group at 3-, 6- and 12 months follow-up was 0 (-1.25 to 2) mmHg, 1 (-1 to 3) mmHg, and 0 (-2.5 to 3) mmHg, respectively. IOP reduction in the study group was statistically significantly larger than in the control group at all follow-ups (p < 0.001). We found a statistically significant difference between the mean number of topical IOP-lowering medications before and at 12 months in the combined surgery group (p < 0.001) as compared to the control group.

Conclusions

This study shows a statistically significant IOP reduction at 3-, 6- and 12 months and reduction of topical IOP-lowering medications at 12 months after combined cataract surgery with iStent inject® W implantation.