Scholarlink

Purpose <p>Laryngeal dystonia (LD), also known as spasmodic dysphonia, is a rare voice production pathology manifested as focal muscle dystonia. The aim of this review is to synthesize current evidence on its aetiology, clinical presentation, diagnostic approach, and available treatment options, while identifying existing knowledge gaps to guide clinical decision-making and future research.</p> Methods <p>A structured literature review was conducted using peer-reviewed articles from medical databases (e.g., PubMed, Google Scholars). Inclusion criteria comprised studies published in English within the last 20&#xa0;years, focusing on LD aetiology, clinical features, diagnosis, or treatment. Both observational studies and clinical trials were included. Exclusion criteria involved case reports with limited applicability, non-English publications, and studies lacking clear diagnostic criteria or therapeutic outcomes.</p> Results <p>Primarily an idiopathic disorder, there is evidence suggesting a neurogenic origin involving basal ganglia dysfunction in LD. Clinically, LD manifests as task-specific voice disturbances, affecting most commonly the adductor muscles (strained voice) or the abductor muscles (breathy voice). Diagnosis is mainly clinical, but supported by laryngoscopic findings and other multidisciplinary evaluation. The gold standard treatment remains botulinum toxin injection, providing symptomatic relief, while voice therapy and, in selected cases, surgical interventions offer adjunctive benefits.</p> Conclusion <p>LD is a neurological voice disorder which requires a high index of suspicion for diagnosis. Individualized treatment, particularly with botulinum toxin, and early recognition, significantly improve patient outcomes. Further research is needed to clarify pathophysiological mechanisms and optimize long-term management strategies.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Laryngeal dystonia: a comprehensive review of aetiology, clinical presentation, diagnosis, and treatment approaches

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年7月16日

查看全文
  • Marius Tudor Ionescu,
  • Maria Dana Morariu,
  • Lucia Popa,
  • Valeria Ionescu,
  • Cristina Țiple,
  • Septimiu Sever Pop,
  • Daniela Vrînceanu,
  • Alma Aurelia Maniu

摘要

Purpose

Laryngeal dystonia (LD), also known as spasmodic dysphonia, is a rare voice production pathology manifested as focal muscle dystonia. The aim of this review is to synthesize current evidence on its aetiology, clinical presentation, diagnostic approach, and available treatment options, while identifying existing knowledge gaps to guide clinical decision-making and future research.

Methods

A structured literature review was conducted using peer-reviewed articles from medical databases (e.g., PubMed, Google Scholars). Inclusion criteria comprised studies published in English within the last 20 years, focusing on LD aetiology, clinical features, diagnosis, or treatment. Both observational studies and clinical trials were included. Exclusion criteria involved case reports with limited applicability, non-English publications, and studies lacking clear diagnostic criteria or therapeutic outcomes.

Results

Primarily an idiopathic disorder, there is evidence suggesting a neurogenic origin involving basal ganglia dysfunction in LD. Clinically, LD manifests as task-specific voice disturbances, affecting most commonly the adductor muscles (strained voice) or the abductor muscles (breathy voice). Diagnosis is mainly clinical, but supported by laryngoscopic findings and other multidisciplinary evaluation. The gold standard treatment remains botulinum toxin injection, providing symptomatic relief, while voice therapy and, in selected cases, surgical interventions offer adjunctive benefits.

Conclusion

LD is a neurological voice disorder which requires a high index of suspicion for diagnosis. Individualized treatment, particularly with botulinum toxin, and early recognition, significantly improve patient outcomes. Further research is needed to clarify pathophysiological mechanisms and optimize long-term management strategies.