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Background <p>Varicella-zoster-virus (VZV) reactivation is a recognized complication following COVID-19 vaccination; however, Ramsay-hunt-syndrome (RHS) rarely has been reported.</p> Case presentation <p>This case presents a 36-year-old immunocompetent man with features of RHS three weeks following the second dose of the BBIBP-CorV (Sinopharm) vaccine. Interestingly, he developed acute unilateral parotitis on his left side and the ultrasonography showed a 55*44*18&#xa0;mm parotid gland with decreased parenchymal echogenicity. He was treated with valacyclovir, and after seven days he was discharged. Also, his parotitis was resolved by day 29 following the presentation of the first symptoms with no further complications.</p> Conclusion <p>The possibility of VZV reactivation after COVID-19 vaccination is an important point and it should be noted that this reactivation might present in unusual clinical scenarios.</p>

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Ramsay-hunt-syndrome associated with unilateral parotitis following COVID-19 vaccine: a case report

  • 期刊论文

  • 发表日期：

    2025年4月2日

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  • Masood Soltanipur,
  • Hossein Yarmohammadi,
  • Seyed Fatah Mahdavi Anari,
  • Mohammadreza Karimi Nemch,
  • Amirmahdi Taromiha,
  • Seyed Davar Siadat

摘要

Background

Varicella-zoster-virus (VZV) reactivation is a recognized complication following COVID-19 vaccination; however, Ramsay-hunt-syndrome (RHS) rarely has been reported.

Case presentation

This case presents a 36-year-old immunocompetent man with features of RHS three weeks following the second dose of the BBIBP-CorV (Sinopharm) vaccine. Interestingly, he developed acute unilateral parotitis on his left side and the ultrasonography showed a 55*44*18 mm parotid gland with decreased parenchymal echogenicity. He was treated with valacyclovir, and after seven days he was discharged. Also, his parotitis was resolved by day 29 following the presentation of the first symptoms with no further complications.

Conclusion

The possibility of VZV reactivation after COVID-19 vaccination is an important point and it should be noted that this reactivation might present in unusual clinical scenarios.