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<p>We aimed to evaluate arterial stiffness parameters, such as the augmentation index (Aix) and pulse wave velocity (PWV), in patients with hidradenitis suppurativa (HS) using an oscillometric arteriograph device and to compare them with healthy individuals. This retrospective study included 70 patients with HS (mean age: 39.2 ± 8.7 years; 63% female) and 70 age- and sex-matched healthy controls (mean age: 38.4 ± 9.1 years; 57% female). Arterial stiffness parameters including PWV and Aix were measured using the Mobil-O-Graph device. Clinical and laboratory data including body mass index (BMI), smoking status, Hurley stage, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and lipid profile were also recorded and compared between groups. PWV was significantly higher in HS patients (8.8 ± 1.3&#xa0;m/s) compared to controls (7.6 ± 1.2&#xa0;m/s; <i>p</i> &lt; 0.001). Similarly, Aix was elevated in HS patients (23.1 ± 7.5%) versus controls (19.9 ± 6.8%; <i>p</i> &lt; 0.05). CRP and ESR levels were significantly higher in the HS group (CRP: 5.2 ± 2.0&#xa0;mg/L vs. 3.1 ± 1.4&#xa0;mg/L, ESR: 21.6 ± 7.9&#xa0;mm/h vs. 12.4 ± 5.6&#xa0;mm/h; <i>p</i> &lt; 0.001 for both). PWV and Aix showed moderate positive correlations with CRP (<i>r</i> = 0.398 and 0.351) and ESR (<i>r</i> = 0.354 and 0.326) (all <i>p</i> &lt; 0.005). HS patients have increased arterial stiffness, closely related to systemic inflammation, despite similar traditional cardiovascular risk factors. Early vascular assessment in HS may aid in cardiovascular risk stratification.</p>

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Evaluation of arterial stiffness parameters in patients with hidradenitis suppurativa using an oscillometric arteriograph

  • 期刊论文

  • 发表日期：

    2026年7月4日

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  • Abdulkadir Arpa,
  • Mehmet Semih Celik

摘要

We aimed to evaluate arterial stiffness parameters, such as the augmentation index (Aix) and pulse wave velocity (PWV), in patients with hidradenitis suppurativa (HS) using an oscillometric arteriograph device and to compare them with healthy individuals. This retrospective study included 70 patients with HS (mean age: 39.2 ± 8.7 years; 63% female) and 70 age- and sex-matched healthy controls (mean age: 38.4 ± 9.1 years; 57% female). Arterial stiffness parameters including PWV and Aix were measured using the Mobil-O-Graph device. Clinical and laboratory data including body mass index (BMI), smoking status, Hurley stage, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and lipid profile were also recorded and compared between groups. PWV was significantly higher in HS patients (8.8 ± 1.3 m/s) compared to controls (7.6 ± 1.2 m/s; p < 0.001). Similarly, Aix was elevated in HS patients (23.1 ± 7.5%) versus controls (19.9 ± 6.8%; p < 0.05). CRP and ESR levels were significantly higher in the HS group (CRP: 5.2 ± 2.0 mg/L vs. 3.1 ± 1.4 mg/L, ESR: 21.6 ± 7.9 mm/h vs. 12.4 ± 5.6 mm/h; p < 0.001 for both). PWV and Aix showed moderate positive correlations with CRP (r = 0.398 and 0.351) and ESR (r = 0.354 and 0.326) (all p < 0.005). HS patients have increased arterial stiffness, closely related to systemic inflammation, despite similar traditional cardiovascular risk factors. Early vascular assessment in HS may aid in cardiovascular risk stratification.