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<p>Rubber accelerator contact allergy is a common cause of glove-related contact dermatitis, especially in occupational settings. While previous studies have reported accelerator presence in medical gloves, discontinuation of gloves due to COVID-19 pandemic-associated supply chain challenges are a current barrier to patient education. The objective of this study was to provide an updated post-COVID-19 guide for medical exam and surgical glove accelerator content in the United States for accelerator-allergic patients based on a manufacturer/company survey. In August 2024, an internet-based search was conducted to compile a list of commercially-available medical examination and surgical gloves. Accelerator ingredients are reported. Nine glove manufacturers were included in the survey, including 142 gloves. 76 gloves were discontinued since the previous analysis, primarily natural rubber latex (NRL) gloves. Dithiocarbamates were the most common accelerator (83.1%), with mercaptobenzothiazole (MBT, 21.8%), and other accelerators present at lower frequencies. The number of gloves labeled as accelerator-free has increased 3-fold since 2016. Altogether, medical examination and surgical glove availability and associated allergen information have changed significantly in the post COVID-19 pandemic supply chain. Accelerators remain common in most medical rubber gloves; however, accelerator-free options are available and patients with these contact allergies should be counseled appropriately.</p>

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Rubber accelerators in medical examination and surgical gloves in the United States: a post-COVID-19 manufacturer/company survey

  • 期刊论文

  • 发表日期：

    2026年4月28日

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  • Mahnoor Mukarram,
  • Brailyn Weber,
  • Samuel F. Ekstein,
  • Dathan Hamann

摘要

Rubber accelerator contact allergy is a common cause of glove-related contact dermatitis, especially in occupational settings. While previous studies have reported accelerator presence in medical gloves, discontinuation of gloves due to COVID-19 pandemic-associated supply chain challenges are a current barrier to patient education. The objective of this study was to provide an updated post-COVID-19 guide for medical exam and surgical glove accelerator content in the United States for accelerator-allergic patients based on a manufacturer/company survey. In August 2024, an internet-based search was conducted to compile a list of commercially-available medical examination and surgical gloves. Accelerator ingredients are reported. Nine glove manufacturers were included in the survey, including 142 gloves. 76 gloves were discontinued since the previous analysis, primarily natural rubber latex (NRL) gloves. Dithiocarbamates were the most common accelerator (83.1%), with mercaptobenzothiazole (MBT, 21.8%), and other accelerators present at lower frequencies. The number of gloves labeled as accelerator-free has increased 3-fold since 2016. Altogether, medical examination and surgical glove availability and associated allergen information have changed significantly in the post COVID-19 pandemic supply chain. Accelerators remain common in most medical rubber gloves; however, accelerator-free options are available and patients with these contact allergies should be counseled appropriately.