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<p>While the name of Sjögren’s syndrome was recently changed to Sjögren’s disease (SjD), the picture of a&#xa0;systemic autoimmune disease with inflammation of the exocrine glands and subsequent dryness has remained unchanged since the first description. This includes a&#xa0;pronounced B‑cell activity with an increased risk of lymphoma, frequent fatigue and arthralgia and relevant organ involvement in some patients. The prevalence in Germany is estimated to be around 7:10,000, slightly higher than for systemic lupus erythematosus (SLE). Women are affected roughly ten times more often than men. The classification criteria are based on antibodies against Ro/SS‑A antigens or a&#xa0;salivary gland biopsy, supplemented by the objective proof of dryness. In view of the now well-established and typical sonographic findings, they could be supplemented by sonographic parameters.</p>

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Krankheitsbild Sjögren-Erkrankung

  • 期刊论文

  • 发表日期：

    2026年3月6日

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  • Martin Aringer,
  • Anne-Kathrin Tausche

摘要

While the name of Sjögren’s syndrome was recently changed to Sjögren’s disease (SjD), the picture of a systemic autoimmune disease with inflammation of the exocrine glands and subsequent dryness has remained unchanged since the first description. This includes a pronounced B‑cell activity with an increased risk of lymphoma, frequent fatigue and arthralgia and relevant organ involvement in some patients. The prevalence in Germany is estimated to be around 7:10,000, slightly higher than for systemic lupus erythematosus (SLE). Women are affected roughly ten times more often than men. The classification criteria are based on antibodies against Ro/SS‑A antigens or a salivary gland biopsy, supplemented by the objective proof of dryness. In view of the now well-established and typical sonographic findings, they could be supplemented by sonographic parameters.