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Purpose <p>To evaluate the clinical outcomes of tubularized incised plate urethroplasty (TIPU) combined with dissection of the urethral plate and distal urethral mobilization in children with mid-to-distal hypospadias.</p> Methods <p>This retrospective study included 183 pediatric patients with hypospadias who underwent primary repair between March 2021 and March 2023. Patients were divided into two groups according to the surgical technique: the modified TIPU group (mTIPU, <i>n</i> = 86) and the conventional TIPU group (cTIPU, <i>n</i> = 97). Baseline characteristics, perioperative parameters, postoperative complications, penile appearance scores, and uroflowmetry parameters were compared between the two groups.</p> Results <p>Baseline characteristics were comparable between the two groups (all <i>P</i> &gt; 0.05). The mTIPU group had a longer operative time and a greater estimated blood loss (EBL) than the cTIPU group (both <i>P</i> &lt; 0.05). However, no statistical difference was observed in the overall incidence of postoperative complications between the groups (<i>P</i> &gt; 0.05). At the 2-year follow-up, patients in the mTIPU group demonstrated higher penile appearance scores for perceived penile straightness and overall appearance (both <i>P</i> &lt; 0.05). In addition, the maximum urinary flow rate (Qmax) and the average urinary flow rate (Qave) were higher, and the duration of micturition was shorter in the mTIPU group compared to the cTIPU group (all <i>P</i> &lt; 0.001), while voided volume did not differ significantly between the two groups (<i>P</i> &gt; 0.05).</p> Conclusion <p>In children with mid-to-distal hypospadias, TIPU combined with urethral plate dissection and distal urethral mobilization may improve postoperative penile appearance and urinary flow parameters. No statistical difference in postoperative complication rates was observed between the two techniques.</p>

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Efficacy of modified tubularized incised plate urethroplasty for hypospadias

  • 期刊论文

  • 发表日期：

    2026年5月11日

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  • Nuoxian Li,
  • Shengli Zhang,
  • Luping Li,
  • Pengpeng Liu,
  • Yuchen Liu,
  • Chunyu Chen,
  • Junxiang Li,
  • Boyuan Wang,
  • Liang Hao,
  • Yasen Wei,
  • Yingzhong Fan

摘要

Purpose

To evaluate the clinical outcomes of tubularized incised plate urethroplasty (TIPU) combined with dissection of the urethral plate and distal urethral mobilization in children with mid-to-distal hypospadias.

Methods

This retrospective study included 183 pediatric patients with hypospadias who underwent primary repair between March 2021 and March 2023. Patients were divided into two groups according to the surgical technique: the modified TIPU group (mTIPU, n = 86) and the conventional TIPU group (cTIPU, n = 97). Baseline characteristics, perioperative parameters, postoperative complications, penile appearance scores, and uroflowmetry parameters were compared between the two groups.

Results

Baseline characteristics were comparable between the two groups (all P > 0.05). The mTIPU group had a longer operative time and a greater estimated blood loss (EBL) than the cTIPU group (both P < 0.05). However, no statistical difference was observed in the overall incidence of postoperative complications between the groups (P > 0.05). At the 2-year follow-up, patients in the mTIPU group demonstrated higher penile appearance scores for perceived penile straightness and overall appearance (both P < 0.05). In addition, the maximum urinary flow rate (Qmax) and the average urinary flow rate (Qave) were higher, and the duration of micturition was shorter in the mTIPU group compared to the cTIPU group (all P < 0.001), while voided volume did not differ significantly between the two groups (P > 0.05).

Conclusion

In children with mid-to-distal hypospadias, TIPU combined with urethral plate dissection and distal urethral mobilization may improve postoperative penile appearance and urinary flow parameters. No statistical difference in postoperative complication rates was observed between the two techniques.