Scholarlink

Background <p>Hepatic cystic echinococcosis (HCE) imposes a significant health burden on children in endemic regions. This meta-analysis compares perioperative outcomes between laparoscopic (LS) and open surgery (OS) for pediatric HCE to inform surgical management strategies.</p> Methods <p>Following PRISMA guidelines, we systematically searched PubMed, CNKI, Wanfang, and VIP for studies (February 2019-April 2024) comparing LS and OS in children with HCE. Two reviewers independently screened studies, extracted data, and assessed quality using the Newcastle-Ottawa Scale. Pooled analysis was performed for operative time, blood loss, hospital stay, biliary complications, residual cavity effusion, and recurrence.</p> Results <p>Eleven studies involving 556 children (LS = 210, OS = 346) were included. LS was associated with significantly reduced intraoperative blood loss (SMD = -1.11, 95% CI: -1.36 to -0.86, <i>P</i> &lt; 0.001) and shorter hospital stay (SMD = -1.12, 95% CI: -1.81 to -0.42, <i>P</i> = 0.002) compared to OS. Operative time was also shorter in the LS group (SMD = -0.36, 95% CI: -0.85 to 0.14, <i>P</i> &lt; 0.001). There were no significant differences in rates of biliary complications (OR = 1.17, 95%CI 0.26–5.35, <i>P</i> = 0.083), residual cavity effusion (OR = 0.34, 95%CI 0.08–1.47, <i>P</i> = 0.149), or recurrence (OR = 0.57, 95%CI 0.21–1.56, <i>P</i> = 0.277).</p> Conclusion <p>For selected pediatric HCE patients, laparoscopic surgery offers faster recovery with less surgical trauma and a comparable safety profile to open surgery. These findings support integrating minimally invasive techniques into pediatric surgical practice in endemic, resource-limited settings.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Laparoscopic versus open surgery for pediatric hepatic cystic echinococcosis in endemic regions: a meta-analysis supporting minimally invasive management

  • 期刊论文

  • 发表日期：

    2026年3月10日

查看全文
  • Sherop Yonten,
  • Sijia Guo,
  • Jiakun Wang,
  • Panden,
  • Tenzin Kinzi,
  • Tsering Lhamo,
  • Sonam Yangzom,
  • Dondan,
  • Sijia Pan,
  • Lan Huang,
  • Wei Zhang,
  • Purpo Tsering,
  • Shuai Li

摘要

Background

Hepatic cystic echinococcosis (HCE) imposes a significant health burden on children in endemic regions. This meta-analysis compares perioperative outcomes between laparoscopic (LS) and open surgery (OS) for pediatric HCE to inform surgical management strategies.

Methods

Following PRISMA guidelines, we systematically searched PubMed, CNKI, Wanfang, and VIP for studies (February 2019-April 2024) comparing LS and OS in children with HCE. Two reviewers independently screened studies, extracted data, and assessed quality using the Newcastle-Ottawa Scale. Pooled analysis was performed for operative time, blood loss, hospital stay, biliary complications, residual cavity effusion, and recurrence.

Results

Eleven studies involving 556 children (LS = 210, OS = 346) were included. LS was associated with significantly reduced intraoperative blood loss (SMD = -1.11, 95% CI: -1.36 to -0.86, P < 0.001) and shorter hospital stay (SMD = -1.12, 95% CI: -1.81 to -0.42, P = 0.002) compared to OS. Operative time was also shorter in the LS group (SMD = -0.36, 95% CI: -0.85 to 0.14, P < 0.001). There were no significant differences in rates of biliary complications (OR = 1.17, 95%CI 0.26–5.35, P = 0.083), residual cavity effusion (OR = 0.34, 95%CI 0.08–1.47, P = 0.149), or recurrence (OR = 0.57, 95%CI 0.21–1.56, P = 0.277).

Conclusion

For selected pediatric HCE patients, laparoscopic surgery offers faster recovery with less surgical trauma and a comparable safety profile to open surgery. These findings support integrating minimally invasive techniques into pediatric surgical practice in endemic, resource-limited settings.