Objectives <p>The aim of the present study was to investigate whether neutrophil–lymphocyte ratio (NLR) and platelet–lymphocyte ratio (PLR) rates have a role in morbidity and mortality in children who were hospitalized due to burns.</p> Methods <p>A total of 282 patients between the ages of 0–18 who were hospitalized due to deep partial thickness and full thickness burns between 2018 and 2023 were included in the study.</p> Results <p>The mean NLR value in deceased patients was found to be significantly higher than that in survivors (<i>p</i> &lt; 0.036). The NLR value was found to be significantly positively associated with the duration of hospital stay (<i>p</i> &lt; 0.001). The sensitivity and specificity of the 8.775 cutoff value for NLR in predicting mortality were determined to be 66.7% and 74.7%, respectively. There was no statistically significant difference between the PLR values of survivors and non-survivors (<i>p</i> = 0.926).</p> Conclusion <p>Despite PLR, the study indicates that the risk of morbidity and mortality is significantly higher in pediatric patients with high NLR values at the time of admission to the hospital, and that the NLR value provides important information about the clinical course and mortality in these patients.</p>

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Neutrophil–lymphocyte ratio and platelet–lymphocyte ratio in morbidity and mortality in children with burns

  • Serap Samut Bülbül,
  • Sevda Akdeniz,
  • Alper Ceylan,
  • Ahmet Saraç,
  • Murat Güzel,
  • Metin Ocak,
  • Selim Görgün

摘要

Objectives

The aim of the present study was to investigate whether neutrophil–lymphocyte ratio (NLR) and platelet–lymphocyte ratio (PLR) rates have a role in morbidity and mortality in children who were hospitalized due to burns.

Methods

A total of 282 patients between the ages of 0–18 who were hospitalized due to deep partial thickness and full thickness burns between 2018 and 2023 were included in the study.

Results

The mean NLR value in deceased patients was found to be significantly higher than that in survivors (p < 0.036). The NLR value was found to be significantly positively associated with the duration of hospital stay (p < 0.001). The sensitivity and specificity of the 8.775 cutoff value for NLR in predicting mortality were determined to be 66.7% and 74.7%, respectively. There was no statistically significant difference between the PLR values of survivors and non-survivors (p = 0.926).

Conclusion

Despite PLR, the study indicates that the risk of morbidity and mortality is significantly higher in pediatric patients with high NLR values at the time of admission to the hospital, and that the NLR value provides important information about the clinical course and mortality in these patients.