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Background <p>Sexual dysfunction (SD) is a common complication in patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), and there remains a lack of objective diagnostic physiological indicators in clinical practice.</p> Objective <p>This study aimed to explore the value of pelvic floor electromyography (PF-EMG) parameters as novel physiological indicators for SD in CP/CPPS patients.</p> Methods <p>A total of 116 CP/CPPS patients were enrolled and stratified into PE and ED subgroups based on validated questionnaires (C-ISFPE and IIEF-5). All participants underwent standardized PF-EMG assessment to evaluate resting tone, fast-twitch, and slow-twitch functions. Statistical analyses included t-tests, logistic regression, and ROC curve analysis.</p> Results <p>In the PE subgroup (<i>n</i> = 66), resting tone was significantly elevated (anterior baseline: 6.49 ± 3.42 µV vs. 3.78 ± 2.79 µV in the non-PE group, <i>P</i> &lt; 0.001) and served as an independent predictor of PE (OR = 1.428, <i>P</i> = 0.003). In the ED subgroup (<i>n</i> = 45), fast-twitch function was severely impaired (rapid contraction: 37.87 ± 18.36 µV vs. 69.92 ± 25.78 µV in the non-ED group, <i>P</i> &lt; 0.001). With a cut-off value of &lt; 45.41 µV for rapid contraction, the area under the curve (AUC) for ED diagnosis was 0.866, with a sensitivity of 92.6%.</p> Conclusion <p>PF-EMG parameters serve as objective, non-invasive physiological indicators that can effectively distinguish between PE and ED subtypes in CP/CPPS patients, paving the way for targeted therapies.</p>

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Pelvic floor electromyographic dysfunction as a novel physiological indicator for subclassifying sexual dysfunction in patients with chronic prostatitis/chronic pelvic pain syndrome

  • 期刊论文

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  • 发表日期：

    2026年2月1日

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  • Shiwei Song,
  • Bin Zhang,
  • Chang Yu,
  • Jinlong Yin,
  • Dehui Chang

摘要

Background

Sexual dysfunction (SD) is a common complication in patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), and there remains a lack of objective diagnostic physiological indicators in clinical practice.

Objective

This study aimed to explore the value of pelvic floor electromyography (PF-EMG) parameters as novel physiological indicators for SD in CP/CPPS patients.

Methods

A total of 116 CP/CPPS patients were enrolled and stratified into PE and ED subgroups based on validated questionnaires (C-ISFPE and IIEF-5). All participants underwent standardized PF-EMG assessment to evaluate resting tone, fast-twitch, and slow-twitch functions. Statistical analyses included t-tests, logistic regression, and ROC curve analysis.

Results

In the PE subgroup (n = 66), resting tone was significantly elevated (anterior baseline: 6.49 ± 3.42 µV vs. 3.78 ± 2.79 µV in the non-PE group, P < 0.001) and served as an independent predictor of PE (OR = 1.428, P = 0.003). In the ED subgroup (n = 45), fast-twitch function was severely impaired (rapid contraction: 37.87 ± 18.36 µV vs. 69.92 ± 25.78 µV in the non-ED group, P < 0.001). With a cut-off value of < 45.41 µV for rapid contraction, the area under the curve (AUC) for ED diagnosis was 0.866, with a sensitivity of 92.6%.

Conclusion

PF-EMG parameters serve as objective, non-invasive physiological indicators that can effectively distinguish between PE and ED subtypes in CP/CPPS patients, paving the way for targeted therapies.