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Purpose <p>To assess the perception and severity of stent-related symptoms (SRS) in patients undergoing retrograde intrarenal surgery (RIRS).</p> Materials and methods <p>A prospective observational study was performed including patients with single or multiple renal stones undergoing ureteral stenting and scheduled for a definitive RIRS. SRS were evaluated at 3 timepoints: pre-operatively on the day of RIRS, as well as on the 1st and 7th postoperative day following RIRS. Bladder pain, back pain, hematuria, urgency, frequency, nocturia, and urge incontinence were evaluated using a visual analog scoring (VAS) system.</p> Results <p>A total of 57 patients were included. The patients reported a significant rise in back pain at day 1 after RIRS (mean rank 2.25 on a scale of 0 to 5) compared to preoperative scores (2.06), with a significant decrease at day 7 following RIRS (1.68) (<i>p</i> = 0.003). A similar pattern was observed for bladder pain, frequency and urge incontinence (all <i>p</i> &lt; 0.001). As for urgency and nocturia, these SRS steadily decreased from baseline to day 1, and in turn from day 1 to day 7 after RIRS (<i>p</i> = 0.004 and <i>p</i> = 0.003, respectively). Hematuria was the only SRS which did not show any significant differences over the 3 evaluated timepoints.</p> Conclusion <p>RIRS temporarily increases certain SRS, particularly pain and urinary discomfort within the first 24&#xa0;h postoperatively. These symptoms tend to improve by the 7th postoperative day, suggesting that surgery itself may contribute to the early symptom burden but ultimately facilitates recovery. Further multi-center prospective studies with bigger sample size are warranted to confirm our findings.</p>

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How does RIRS impact on stent-related symptoms? Insights from a prospective observational study by EAU-YAU endourology and urolithiasis working group

  • 期刊论文

  • 发表日期：

    2025年11月10日

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  • Arman Tsaturyan,
  • Etienne Xavier Keller,
  • Stefano Mancon,
  • Hayk Grigoryan,
  • Tarik Emre Sener,
  • Eugenio Ventimiglia,
  • Francesco Esperto,
  • Vincent De Coninck,
  • Patrick Juliebø-Jones,
  • Begona Ballesta Martinez,
  • Ioannis Mykoniatis,
  • Alba Sierra Del Rio,
  • Lazaros Tzelves,
  • Alberto Olivero,
  • Mariela Corrales,
  • Victoria Jahrreiss,
  • Ali Talyshinskii,
  • Matthias Boeykens,
  • Rifat Ergul,
  • Lukasz Nowak,
  • Amelia Pietropaolo

摘要

Purpose

To assess the perception and severity of stent-related symptoms (SRS) in patients undergoing retrograde intrarenal surgery (RIRS).

Materials and methods

A prospective observational study was performed including patients with single or multiple renal stones undergoing ureteral stenting and scheduled for a definitive RIRS. SRS were evaluated at 3 timepoints: pre-operatively on the day of RIRS, as well as on the 1st and 7th postoperative day following RIRS. Bladder pain, back pain, hematuria, urgency, frequency, nocturia, and urge incontinence were evaluated using a visual analog scoring (VAS) system.

Results

A total of 57 patients were included. The patients reported a significant rise in back pain at day 1 after RIRS (mean rank 2.25 on a scale of 0 to 5) compared to preoperative scores (2.06), with a significant decrease at day 7 following RIRS (1.68) (p = 0.003). A similar pattern was observed for bladder pain, frequency and urge incontinence (all p < 0.001). As for urgency and nocturia, these SRS steadily decreased from baseline to day 1, and in turn from day 1 to day 7 after RIRS (p = 0.004 and p = 0.003, respectively). Hematuria was the only SRS which did not show any significant differences over the 3 evaluated timepoints.

Conclusion

RIRS temporarily increases certain SRS, particularly pain and urinary discomfort within the first 24 h postoperatively. These symptoms tend to improve by the 7th postoperative day, suggesting that surgery itself may contribute to the early symptom burden but ultimately facilitates recovery. Further multi-center prospective studies with bigger sample size are warranted to confirm our findings.