Evaluation of antimicrobial and anti-cancer activity of Zn²⁺ doped cobalt ferrite (Co_1-xZn_xFe₂O₄) magnetic nanoparticles prepared by self-sustained solution combustion synthesis (SCS)

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发表日期：

2025年5月12日

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K. Venkatesan,
D. Rajan Babu,
R. Vidya

摘要

Zn²⁺-doped cobalt ferrite nanoparticles were prepared by the solution combustion method using hexamine as fuel. The observed X-ray diffraction patterns were shifted slightly when increasing the concentration of Zn²⁺ ions because the structure was shrank. The structural parameters were modified by changing the concentration of Zn²⁺ ions. The porous nature of the as-synthesized samples was confirmed by scanning electron micrographs. Magnetization was increased from 42 to 63 emu/g with the increasing concentration of Zn²⁺ ions in cobalt ferrite nanoparticles. Antimicrobial activity was assessed against the Co_1-xZn_xFe₂O₄ magnetic nanoparticles, and it was confirmed that the prepared material could be used as an antimicrobial agent. It was found that 50% of cancer cells were inhibited by using 600 μg/ml Co_0.8Zn_0.2Fe₂O₄ magnetic nanoparticles (IC₅₀).

Evaluation of antimicrobial and anti-cancer activity of Zn2+ doped cobalt ferrite (Co1-xZnxFe2O4) magnetic nanoparticles prepared by self-sustained solution combustion synthesis (SCS)

摘要

Evaluation of antimicrobial and anti-cancer activity of Zn²⁺ doped cobalt ferrite (Co_1-xZn_xFe₂O₄) magnetic nanoparticles prepared by self-sustained solution combustion synthesis (SCS)