Objectives To evaluate whether temporal AI-assisted compressed sensing (tACS) enables high-resolution, motion-robust magnetic resonance enterography (MRE) without antiperistaltic agents and improves acquisition efficiency and motility visualization. Materials and methods This prospective single-center study enrolled consecutive patients who underwent both routine and tACS MRE on a 3.0-T scanner between October 2024 and June 2025, without antiperistaltic agents. The tACS protocol acquired axial and coronal T2-weighted images (T2WI); the routine protocol included a coronal Cine sequence. Acquisition time and total temporal frames for non-fat-saturated T2WI (routine and tACS) and Cine were recorded to calculate imaging efficiency (frames/min). Primary outcomes included total temporal frames, scan time, efficiency, subjective image-quality scores, apparent signal-to-noise ratio (aSNR), contrast-to-noise ratio (aCNR), maximum local variation sharpness, peri-enteric fat-plane clarity, and ileocecal-valve (ICV) motility. Paired statistical tests compared within-subject differences; Kendall’s W assessed inter-reader agreement. Results Thirty patients completed both protocols. tACS acquired 504 frames in 287 s vs 107 frames in 241 s for the routine protocol, improving efficiency 4.0-fold (105.4 vs 26.6 frames/min; p < 0.001). Subjective image quality favored tACS (median 5.0 vs ≤ 4.0; p < 0.01) with perfect agreement (W = 1.00). Quantitative analysis demonstrated significantly improved sharpness (all p < 0.001) and increased aSNR/aCNR. Fat-plane clarity reached perfect scores in 93% (28/30) with tACS, and ICV motility scoring was superior to Cine (median 3.0 vs 2.0; p < 0.001). Conclusions tACS enhances temporal resolution and image quality for MRE without antiperistaltic agents, with minimal extra scan time and potential to simplify clinical workflows. Key Points <Emphasis Type="BoldItalic">Question</Emphasis> Can tACS provide high-resolution, motion-robust MRE images without the need for antiperistaltic agents? <Emphasis Type="BoldItalic">Findings</Emphasis> tACS improved imaging efficiency four-fold while significantly enhancing subjective image quality, sharpness, and motility visualization compared to routine protocols. <Emphasis Type="BoldItalic">Clinical relevance</Emphasis> tACS enables high-quality MRE without antiperistaltic medication, with the potential to simplify clinical workflows, improve patient comfort, and support reliable visualization of bowel motility. Graphical Abstract

Temporal AI-assisted compressed sensing for high-resolution, motion-robust small-bowel MR enterography without antiperistaltic agents: a feasibility study

期刊论文
发表日期：

2026年4月3日

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Ziman Xiong,
Yufan Wang,
Liya Ma,
Xiaopeng Song,
Wei Mao,
Zhen Li,
Yaqi Shen

摘要

Objectives

To evaluate whether temporal AI-assisted compressed sensing (tACS) enables high-resolution, motion-robust magnetic resonance enterography (MRE) without antiperistaltic agents and improves acquisition efficiency and motility visualization.

Materials and methods

This prospective single-center study enrolled consecutive patients who underwent both routine and tACS MRE on a 3.0-T scanner between October 2024 and June 2025, without antiperistaltic agents. The tACS protocol acquired axial and coronal T2-weighted images (T2WI); the routine protocol included a coronal Cine sequence. Acquisition time and total temporal frames for non-fat-saturated T2WI (routine and tACS) and Cine were recorded to calculate imaging efficiency (frames/min). Primary outcomes included total temporal frames, scan time, efficiency, subjective image-quality scores, apparent signal-to-noise ratio (aSNR), contrast-to-noise ratio (aCNR), maximum local variation sharpness, peri-enteric fat-plane clarity, and ileocecal-valve (ICV) motility. Paired statistical tests compared within-subject differences; Kendall’s W assessed inter-reader agreement.

Results

Thirty patients completed both protocols. tACS acquired 504 frames in 287 s vs 107 frames in 241 s for the routine protocol, improving efficiency 4.0-fold (105.4 vs 26.6 frames/min; p < 0.001). Subjective image quality favored tACS (median 5.0 vs ≤ 4.0; p < 0.01) with perfect agreement (W = 1.00). Quantitative analysis demonstrated significantly improved sharpness (all p < 0.001) and increased aSNR/aCNR. Fat-plane clarity reached perfect scores in 93% (28/30) with tACS, and ICV motility scoring was superior to Cine (median 3.0 vs 2.0; p < 0.001).

Conclusions

tACS enhances temporal resolution and image quality for MRE without antiperistaltic agents, with minimal extra scan time and potential to simplify clinical workflows.

Key Points

Question Can tACS provide high-resolution, motion-robust MRE images without the need for antiperistaltic agents?

Findings tACS improved imaging efficiency four-fold while significantly enhancing subjective image quality, sharpness, and motility visualization compared to routine protocols.

Clinical relevance tACS enables high-quality MRE without antiperistaltic medication, with the potential to simplify clinical workflows, improve patient comfort, and support reliable visualization of bowel motility.

Graphical Abstract