Scholarlink

Abstract <p>Perfusion MRI techniques—including dynamic susceptibility contrast (DSC) MRI, dynamic contrast-enhanced (DCE) MRI, arterial spin labeling (ASL) MRI, and intravoxel incoherent motion (IVIM) MRI—hold strong potential as imaging techniques for diagnosing, staging, and monitoring disease across a range of clinical applications. However, clinical adoption, especially of quantitative parameters, remains variable across techniques. Key barriers to broader implementation include a lack of standardized acquisition and analysis protocols, leading to poor reproducibility and reduced clinical confidence. Additionally, limited awareness and understanding of certain techniques among radiologists contribute to underutilization in practice. This work provides practice recommendations to support radiologists in integrating perfusion MRI into routine clinical workflows. It includes guidance on technique selection, acquisition, and analysis, supported by a flowchart outlining typical imaging pathways. These efforts align with ongoing initiatives such as the Quantitative Medical Imaging Coalition (formerly QIBA) and the ISMRM Open Science Initiative for Perfusion Imaging (OSIPI), which are developing standards and tools to enhance reproducibility and clinical utility. Ultimately, the successful adoption of state-of-the-art perfusion MRI depends on close collaboration between clinicians, researchers, and industry stakeholders to ensure robust, standardized, and clinically meaningful application.</p> Key Points <p><UnorderedList Mark="Bullet"> <ItemContent> <p><i>Perfusion MRI parameters hold great promise as imaging biomarkers, but their clinical adoption, especially of quantitative parameters, remains variable across perfusion MRI techniques</i>.</p> </ItemContent> <ItemContent> <p><i>An overview of perfusion MRI techniques, explaining the physics, illustrating clinical applications, and addressing common technical challenges, is provided to support perfusion MRI use in clinical practice</i>.</p> </ItemContent> <ItemContent> <p><i>Successful adoption of state-of-the-art perfusion MRI depends on close collaboration between clinicians, researchers, and industry stakeholders to ensure robust, standardized, and clinically meaningful applications for patient care</i>.</p> </ItemContent> </UnorderedList></p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

ESR Essentials: Perfusion MRI—practice recommendations by the European Society for Magnetic Resonance in Medicine and Biology

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年1月27日

查看全文
  • Petra J. van Houdt,
  • Lena Václavů,
  • Steven Sourbron,
  • Eve S. Shalom,
  • Christian Federau,
  • Mami Iima,
  • Mira M. Liu,
  • Linda Knutsson,
  • Ronnie Wirestam,
  • Matthias Günther,
  • Matthias J. P. van Osch,
  • Rianne A. van der Heijden

摘要

Abstract

Perfusion MRI techniques—including dynamic susceptibility contrast (DSC) MRI, dynamic contrast-enhanced (DCE) MRI, arterial spin labeling (ASL) MRI, and intravoxel incoherent motion (IVIM) MRI—hold strong potential as imaging techniques for diagnosing, staging, and monitoring disease across a range of clinical applications. However, clinical adoption, especially of quantitative parameters, remains variable across techniques. Key barriers to broader implementation include a lack of standardized acquisition and analysis protocols, leading to poor reproducibility and reduced clinical confidence. Additionally, limited awareness and understanding of certain techniques among radiologists contribute to underutilization in practice. This work provides practice recommendations to support radiologists in integrating perfusion MRI into routine clinical workflows. It includes guidance on technique selection, acquisition, and analysis, supported by a flowchart outlining typical imaging pathways. These efforts align with ongoing initiatives such as the Quantitative Medical Imaging Coalition (formerly QIBA) and the ISMRM Open Science Initiative for Perfusion Imaging (OSIPI), which are developing standards and tools to enhance reproducibility and clinical utility. Ultimately, the successful adoption of state-of-the-art perfusion MRI depends on close collaboration between clinicians, researchers, and industry stakeholders to ensure robust, standardized, and clinically meaningful application.

Key Points

Perfusion MRI parameters hold great promise as imaging biomarkers, but their clinical adoption, especially of quantitative parameters, remains variable across perfusion MRI techniques.

An overview of perfusion MRI techniques, explaining the physics, illustrating clinical applications, and addressing common technical challenges, is provided to support perfusion MRI use in clinical practice.

Successful adoption of state-of-the-art perfusion MRI depends on close collaboration between clinicians, researchers, and industry stakeholders to ensure robust, standardized, and clinically meaningful applications for patient care.