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<p>Exercise is a key non-pharmacological component of therapy in axial spondyloarthritis (axSpA). Evidence for yoga as a mind–body intervention remains limited. This study aimed to assess the effects of an 8-week yoga program on mobility, function, disease activity, activity-related competences, and psychological outcomes in axSpA compared with physiotherapy and healthy individuals.&#xa0;We conducted a prospective, non-randomized, study (University Hospital Erlangen, May 2021–January 2024). AxSpA patients participated either in weekly yoga sessions for 8&#xa0;weeks (approximately 60&#xa0;min; online format) or received standard individual physiotherapy (≥ 30&#xa0;min/week). A healthy control group completed the same yoga program. Health related outcomes at baseline and follow-up were measured and changes were analysed using linear mixed-effects models.&#xa0;Seventy-six participants were included. In axSpA, spinal mobility improved in the yoga group (BASMI Δ − 0.31; p = 0.002), while the physiotherapy group worsened (Δ + 0.29; p = 0.003). Physical activity related health competency (control competence Δ + 1.10; p = 0.001; self-regulation Δ + 0.72; p = 0.021) and psychological outcomes improved in the yoga group with increased quality of life mental scores (Δ + 6.62; p &lt; 0.001) and reduced kinesiophobia (TSK Δ − 3.25; p = 0.008); physiotherapy showed no meaningful changes. Disease activity showed a significant decrease in the yoga group (BASDAI Δ –0.44; p = 0.049). Healthy individuals showed similar directional changes with smaller effects.&#xa0;An 8-week yoga intervention was associated with improvements in mobility, psychological outcomes and activity-related competences. Findings support yoga as a complementary treatment addressing both physical and psychological dimensions of axSpA.&#xa0;The study was registered in the German Clinical Trials Register (DRKS-ID: DRKS00025215). </p>

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Impact of Yoga on Spinal Mobility and Psychological Outcomes in Patients with Axial Spondyloarthritis: A Prospective Non-randomized Controlled Study

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年6月22日

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  • Vanessa Bundle,
  • Claudia Bouzas,
  • Alp Temiz,
  • Birte Coppers,
  • Ines Ebner,
  • Paloma Palm von Alten Blaskowitz,
  • Sebastian Rudolf,
  • Anna-Maria Liphardt,
  • Maria Gabriella Raimondo,
  • Andreas Wirsching,
  • Elizabeth Araujo,
  • Filippo Fagni,
  • Andreas Ramming,
  • Georg Schett,
  • Harriet Morf

摘要

Exercise is a key non-pharmacological component of therapy in axial spondyloarthritis (axSpA). Evidence for yoga as a mind–body intervention remains limited. This study aimed to assess the effects of an 8-week yoga program on mobility, function, disease activity, activity-related competences, and psychological outcomes in axSpA compared with physiotherapy and healthy individuals. We conducted a prospective, non-randomized, study (University Hospital Erlangen, May 2021–January 2024). AxSpA patients participated either in weekly yoga sessions for 8 weeks (approximately 60 min; online format) or received standard individual physiotherapy (≥ 30 min/week). A healthy control group completed the same yoga program. Health related outcomes at baseline and follow-up were measured and changes were analysed using linear mixed-effects models. Seventy-six participants were included. In axSpA, spinal mobility improved in the yoga group (BASMI Δ − 0.31; p = 0.002), while the physiotherapy group worsened (Δ + 0.29; p = 0.003). Physical activity related health competency (control competence Δ + 1.10; p = 0.001; self-regulation Δ + 0.72; p = 0.021) and psychological outcomes improved in the yoga group with increased quality of life mental scores (Δ + 6.62; p < 0.001) and reduced kinesiophobia (TSK Δ − 3.25; p = 0.008); physiotherapy showed no meaningful changes. Disease activity showed a significant decrease in the yoga group (BASDAI Δ –0.44; p = 0.049). Healthy individuals showed similar directional changes with smaller effects. An 8-week yoga intervention was associated with improvements in mobility, psychological outcomes and activity-related competences. Findings support yoga as a complementary treatment addressing both physical and psychological dimensions of axSpA. The study was registered in the German Clinical Trials Register (DRKS-ID: DRKS00025215).