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<p>Xanthan gum (XG) is a biopolymer that is derived naturally and has received significant attention from the biomedical and pharmaceutical fields due to its exceptional properties. It is known for its biocompatibility, biodegradability, and versatility. It is extracted through fermentation of simple sugars, and its name is derived from <i>Xanthomonas campestris</i>, i.e., the species of bacteria used. It is an extensively used compound across different industries as a thickening agent in the food industry, thickening drilling mud in the oil industry, and water gels in the cosmetic industry. Further, this review highlights the diverse applications of XG in anticancer, antibacterial, and antifungal activity. It also gives insight into the bone tissue regeneration properties associated with XG. This review discusses about various innovative uses, such as hydrogels, nanoparticles, etc., incorporated with XG to enhance its purpose. Although there are certain limitations with each innovative advancement of XG in the biomedical field, some cause certain side effects and do not prove to be as effective, along with cost inefficiency. Overall, the recent advancements on XG for various purposes have provided promising results in biomedical and pharmaceutical applications, with further ongoing research still going on even now. Graphical abstract:&#xa0;“Xanthan Gum”, a multifunctional biopolymer for advanced drug delivery &amp; regenerative applications.</p> Graphical Abstract <p></p>

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Xanthan gum as a multifunctional biopolymer: exploring its antibacterial, antifungal, anticancer, and bone tissue regeneration applications

  • 期刊论文

  • 发表日期：

    2026年4月22日

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  • S. Emily Raj,
  • Vismaya Aranneri,
  • Payal Damgude,
  • Imran Uddin,
  • Jaya Lakkakula

摘要

Xanthan gum (XG) is a biopolymer that is derived naturally and has received significant attention from the biomedical and pharmaceutical fields due to its exceptional properties. It is known for its biocompatibility, biodegradability, and versatility. It is extracted through fermentation of simple sugars, and its name is derived from Xanthomonas campestris, i.e., the species of bacteria used. It is an extensively used compound across different industries as a thickening agent in the food industry, thickening drilling mud in the oil industry, and water gels in the cosmetic industry. Further, this review highlights the diverse applications of XG in anticancer, antibacterial, and antifungal activity. It also gives insight into the bone tissue regeneration properties associated with XG. This review discusses about various innovative uses, such as hydrogels, nanoparticles, etc., incorporated with XG to enhance its purpose. Although there are certain limitations with each innovative advancement of XG in the biomedical field, some cause certain side effects and do not prove to be as effective, along with cost inefficiency. Overall, the recent advancements on XG for various purposes have provided promising results in biomedical and pharmaceutical applications, with further ongoing research still going on even now. Graphical abstract: “Xanthan Gum”, a multifunctional biopolymer for advanced drug delivery & regenerative applications.

Graphical Abstract