<p>As an antioxidant biopolymer, chitosan nanoparticles can be conjugated with other antioxidant agents to increase the potential applications of the resulting materials in a variety of sectors, including food, packaging, cosmetics, and other industries. In this research, terephthaldialdehyde was used to quickly create a novel oxime. The oxime was then connected to chitosan nanoparticles (CSNP) to acquire established biological characteristics. FTIR, <sup>1</sup>H and <sup>13</sup>C NMR all demonstrated the oxime’s production. The Schiff base of oxime on chitosan nanoparticles (CSNP-OX) was detected by FTIR, UV-Vis, DLS, FE-SEM-EDX, and TEM. The antioxidant activities of the CSNP and CSNP-OX were also analyzed; DPPH radical scavenging of CSNP-OX was higher than CSNP. These findings suggest that the CSNP-OX is a viable option for utilization in pharmaceuticals and food items for innovative uses.</p>

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Modification of chitosan nanoparticle by a new oxime compound: synthesis, characterization, and antioxidant activities

  • Atefeh Sabzevari,
  • Ali Kakanejadifard

摘要

As an antioxidant biopolymer, chitosan nanoparticles can be conjugated with other antioxidant agents to increase the potential applications of the resulting materials in a variety of sectors, including food, packaging, cosmetics, and other industries. In this research, terephthaldialdehyde was used to quickly create a novel oxime. The oxime was then connected to chitosan nanoparticles (CSNP) to acquire established biological characteristics. FTIR, 1H and 13C NMR all demonstrated the oxime’s production. The Schiff base of oxime on chitosan nanoparticles (CSNP-OX) was detected by FTIR, UV-Vis, DLS, FE-SEM-EDX, and TEM. The antioxidant activities of the CSNP and CSNP-OX were also analyzed; DPPH radical scavenging of CSNP-OX was higher than CSNP. These findings suggest that the CSNP-OX is a viable option for utilization in pharmaceuticals and food items for innovative uses.