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<p>We build and study an individual based model of the telomere length’s evolution in a population across multiple generations. This model is a continuous time typed branching process, where the type of an individual includes its gamete mean telomere length and its age. We study its Malthusian’s behaviour and provide numerical simulations to understand the influence of biologically relevant parameters.</p>

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A branching model for intergenerational telomere length dynamics

  • 期刊论文

  • 发表日期：

    2025年1月26日

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  • Athanasios Benetos,
  • Olivier Coudray,
  • Anne Gégout-Petit,
  • Lionel Lenôtre,
  • Simon Toupance,
  • Denis Villemonais

摘要

We build and study an individual based model of the telomere length’s evolution in a population across multiple generations. This model is a continuous time typed branching process, where the type of an individual includes its gamete mean telomere length and its age. We study its Malthusian’s behaviour and provide numerical simulations to understand the influence of biologically relevant parameters.