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<p><i>Pseudomonas juntendi</i> is a newly recognized opportunistic pathogen often exhibiting multi-drug resistance and commonly isolated from clinical settings. Here, we report the characterization of <i>P. juntendi</i> strain A3e, isolated from irrigation water, which was analyzed using antimicrobial susceptibility testing and whole-genome sequencing. Taxonomic classification via multi-locus sequence typing and average nucleotide identity analysis confirmed the strain’s identity as <i>P. juntendi</i> with over 99% similarity. Phenotypic testing revealed strong biofilm formation and resistance to four antibiotics and intermediate resistance to two additional antibiotics. Genomic analysis identified 24 antibiotic-resistance genes, predominantly related to efflux pumps, and 50 virulence-related genes involved in adhesion, motility, biofilm formation, and siderophore uptake. This is the first genome of <i>P. juntendi</i> reported in Mexico; despite its environmental origin, the potential clinical implications warrant attention. </p>

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Genomic and Phenotypic Characterization of Pseudomonas juntendi Strain A3e, a Drug-Resistant Isolate from Irrigation Water

  • 期刊论文

  • 发表日期：

    2025年7月24日

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  • Ángel Ibarra-Rodríguez,
  • Jean Pierre González-Gómez,
  • Manuel Ángel Castillo-Olea,
  • Bruno Gomez-Gil,
  • Nohelia Castro-del Campo,
  • Cristobal Chaidez

摘要

Pseudomonas juntendi is a newly recognized opportunistic pathogen often exhibiting multi-drug resistance and commonly isolated from clinical settings. Here, we report the characterization of P. juntendi strain A3e, isolated from irrigation water, which was analyzed using antimicrobial susceptibility testing and whole-genome sequencing. Taxonomic classification via multi-locus sequence typing and average nucleotide identity analysis confirmed the strain’s identity as P. juntendi with over 99% similarity. Phenotypic testing revealed strong biofilm formation and resistance to four antibiotics and intermediate resistance to two additional antibiotics. Genomic analysis identified 24 antibiotic-resistance genes, predominantly related to efflux pumps, and 50 virulence-related genes involved in adhesion, motility, biofilm formation, and siderophore uptake. This is the first genome of P. juntendi reported in Mexico; despite its environmental origin, the potential clinical implications warrant attention.