Purpose <p>The intracranial venous system is characterized by a great variability both in anatomic and functional issues. In particular, the supratentorial venous system is distinguished in the adult configuration in a deep and superficial pathway. The communication between these two compartments is provided by the so-called transcerebral veins, tiny venous channels connecting the deep medullary veins with the superficial medullary veins. No further connection between the two systems has been described in the literature.</p> Methods <p>We are presenting an incidental finding in a patient undergoing brain Magnetic Resonance Imaging (MRI) in the diagnostic work-up of headache of migraine type. In fact, a hyperintense linear signal change in the white matter of the right hemisphere was identified, connecting the subependymal periventricular region with the pial surface and associated with a Susceptibility Weighted Imaging (SWI) appearance of a long venous channel continuing the course of the lateral thalamostriate vein. No further changes were identified and neuronal migration anomalies were absent.</p> Conclusions <p>We described a new type of connection between deep and superficial venous system, different from the transcerebral veins, and we called it transmantle vein, detailing anatomic and embryologic remarks.</p>