Scholarlink

<p>This systematic review and meta-analysis evaluated pain and functional outcomes, safety, and differences between embolic agents in genicular artery embolization (GAE) for knee osteoarthritis. Forty-five studies including 2205 patients were analyzed. Across predominantly uncontrolled studies, clinically relevant improvements were observed, with pooled Visual Analogue Scale reductions of − 37.5 points at 1&#xa0;month and − 37.1 at 12&#xa0;months. Western Ontario and McMaster Universities Osteoarthritis Index improved by − 28.9 at 1&#xa0;month, and Knee Injury and Osteoarthritis Outcome Score-Pain by + 23.6 at 6&#xa0;months. Mean changes exceeded clinically important thresholds. No significant subgroup interaction between permanent and temporary embolic agents was observed. The most frequent adverse events were transient skin discoloration (11%) and hematoma (3%). Overall, the certainty of evidence ranged from very low to low.</p><p><b>Graphical Abstract</b></p><p></p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Outcome and Safety of Genicular Artery Embolization for Knee Osteoarthritis: A Systematic Review and Meta-Analysis

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年6月16日

查看全文
  • Arian Taheri Amin,
  • Isaac Eli Martínez Safar,
  • Ricardo Baquero Trujillo,
  • Juan Guillermo Trujillo Buritica,
  • Osman Ahmed,
  • Kai Jannusch,
  • Peter Minko

摘要

This systematic review and meta-analysis evaluated pain and functional outcomes, safety, and differences between embolic agents in genicular artery embolization (GAE) for knee osteoarthritis. Forty-five studies including 2205 patients were analyzed. Across predominantly uncontrolled studies, clinically relevant improvements were observed, with pooled Visual Analogue Scale reductions of − 37.5 points at 1 month and − 37.1 at 12 months. Western Ontario and McMaster Universities Osteoarthritis Index improved by − 28.9 at 1 month, and Knee Injury and Osteoarthritis Outcome Score-Pain by + 23.6 at 6 months. Mean changes exceeded clinically important thresholds. No significant subgroup interaction between permanent and temporary embolic agents was observed. The most frequent adverse events were transient skin discoloration (11%) and hematoma (3%). Overall, the certainty of evidence ranged from very low to low.

Graphical Abstract