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Purpose <p>To describe the technique and evaluate the safety and clinical efficacy of CT-guided thermal ablation for postoperative isolated bile leakage (IBL) in patients with disconnected bile ducts.</p> Materials and Methods <p>This retrospective study included 14 patients with postoperative IBL following liver resection between 2016 and 2024. All patients underwent CT-guided radiofrequency ablation (RFA) as treatment for IBL. Technical success was defined as appropriate coverage of the leakage site on post-ablation CT. Clinical success was defined as cessation of IBL; time to leak cessation was recorded accordingly. Total percutaneous biloma drainage time and peri-/post-interventional complications were evaluated accordingly.</p> Results <p>Technical success was achieved in all ablation procedures with no major adverse events. Clinical success was observed in 93% (<i>n</i> = 13) of patients. One patient experienced recurrence of IBL within 30&#xa0;days. Median total drainage time was 33.5 (IQR 20–62) days. The median time to leak cessation after RFA was 4.5 (IQR 4–6) days.</p> Conclusion <p>CT-guided thermal ablation appears to be an effective and safe treatment option for postoperative IBL, helping to reduce the duration of drainage therapy.</p> Graphical Abstract <p></p>

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CT-guided Thermal Ablation of Postoperative Isolated Bile Leakages—Evaluation of Safety and Therapeutic Effectiveness

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年12月7日

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  • Clarissa Hosse,
  • Johannes Kolck,
  • Felix Krenzien,
  • Timo A. Auer,
  • Dominik Geisel,
  • Wenzel Schöning,
  • Bernhard Gebauer,
  • Uli Fehrenbach

摘要

Purpose

To describe the technique and evaluate the safety and clinical efficacy of CT-guided thermal ablation for postoperative isolated bile leakage (IBL) in patients with disconnected bile ducts.

Materials and Methods

This retrospective study included 14 patients with postoperative IBL following liver resection between 2016 and 2024. All patients underwent CT-guided radiofrequency ablation (RFA) as treatment for IBL. Technical success was defined as appropriate coverage of the leakage site on post-ablation CT. Clinical success was defined as cessation of IBL; time to leak cessation was recorded accordingly. Total percutaneous biloma drainage time and peri-/post-interventional complications were evaluated accordingly.

Results

Technical success was achieved in all ablation procedures with no major adverse events. Clinical success was observed in 93% (n = 13) of patients. One patient experienced recurrence of IBL within 30 days. Median total drainage time was 33.5 (IQR 20–62) days. The median time to leak cessation after RFA was 4.5 (IQR 4–6) days.

Conclusion

CT-guided thermal ablation appears to be an effective and safe treatment option for postoperative IBL, helping to reduce the duration of drainage therapy.

Graphical Abstract