Scholarlink

Background <p>Lower eyelid aging manifests as several distinct issues, including tear trough deformities, eye bags (with or without skin laxity), and infraorbital dark circles. As lower eyelid aging represents a complex and multifactorial problem, the current approaches, relying on a single surgical technique or injection of single product, often yield unsatisfactory results. The present study describes a simplified strategy utilizing fat derivatives transplantation: the Pyramidal Multi-type, Multi-method, and Multi-layer (3M) strategy. This approach achieved favorable outcomes by simultaneously addressing all these lower eyelid aging problems.</p> Methods <p>This study included 53 patients (106 sides), with a median follow-up of 15.5&#xa0;months (range from 6 to 24&#xa0;months). All patients received Pyramidal 3M fat grafting for lower eyelid aging by deep transplantation of macrofat, superficial transplantation of microfat or microfat/superficial enhanced fluid fat (SEFF), and subdermal transplantation of nanofat or stromal vascular fraction (SVF). We retrospectively analyzed the histories and photographs of patients who underwent Pyramidal 3M fat grafting for lower eyelid aging. Patients were followed up before and 6&#xa0;months after the treatments by modified Goldberg scale and subject satisfaction assessment (SSA) scale.</p> Results <p>Only mild adverse effects such as mild edema and transient ecchymosis were observed, occurring in 3.8% of patients. More severe complications like infections, calcification, fibrosis, fat liquefaction, visible grafts, occlusion of the ophthalmic artery, or vision loss were not encountered in any participants. 11 patients (22 sides) underwent revision surgery 3-6 months after the initial procedure due to suboptimal outcomes. Both the Goldberg scale and SSA scale demonstrated statistically significant improvements to varying degrees.</p> Conclusion <p>The Pyramidal 3M autologous fat grafting strategy provides a convenient, effective, and safe solution for infraorbital rejuvenation in middle-aged patients, with rapid recovery. This technique effectively addresses tear trough deformities, mild eye bags (without skin laxity), and dark circles.</p> Level of Evidence IV <p>This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors <a href="http://www.springer.com/00266">www.springer.com/00266</a>.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Novel Treatment of Pyramidal Multi-Type, Multi-Method, and Multi-Layer (3M) Autologous Fat Grafting Strategy for Infraorbital Aging

  • 期刊论文

  • 发表日期：

    2026年1月22日

查看全文
  • Jie Zhu,
  • Yingshen Shi,
  • Xiaoyan Yu,
  • Jianghui Ying,
  • Lu Lu,
  • Zuochao Yao,
  • Qianhui Xu,
  • Xuemei Wu,
  • Hua Jiang,
  • Hui Wang

摘要

Background

Lower eyelid aging manifests as several distinct issues, including tear trough deformities, eye bags (with or without skin laxity), and infraorbital dark circles. As lower eyelid aging represents a complex and multifactorial problem, the current approaches, relying on a single surgical technique or injection of single product, often yield unsatisfactory results. The present study describes a simplified strategy utilizing fat derivatives transplantation: the Pyramidal Multi-type, Multi-method, and Multi-layer (3M) strategy. This approach achieved favorable outcomes by simultaneously addressing all these lower eyelid aging problems.

Methods

This study included 53 patients (106 sides), with a median follow-up of 15.5 months (range from 6 to 24 months). All patients received Pyramidal 3M fat grafting for lower eyelid aging by deep transplantation of macrofat, superficial transplantation of microfat or microfat/superficial enhanced fluid fat (SEFF), and subdermal transplantation of nanofat or stromal vascular fraction (SVF). We retrospectively analyzed the histories and photographs of patients who underwent Pyramidal 3M fat grafting for lower eyelid aging. Patients were followed up before and 6 months after the treatments by modified Goldberg scale and subject satisfaction assessment (SSA) scale.

Results

Only mild adverse effects such as mild edema and transient ecchymosis were observed, occurring in 3.8% of patients. More severe complications like infections, calcification, fibrosis, fat liquefaction, visible grafts, occlusion of the ophthalmic artery, or vision loss were not encountered in any participants. 11 patients (22 sides) underwent revision surgery 3-6 months after the initial procedure due to suboptimal outcomes. Both the Goldberg scale and SSA scale demonstrated statistically significant improvements to varying degrees.

Conclusion

The Pyramidal 3M autologous fat grafting strategy provides a convenient, effective, and safe solution for infraorbital rejuvenation in middle-aged patients, with rapid recovery. This technique effectively addresses tear trough deformities, mild eye bags (without skin laxity), and dark circles.

Level of Evidence IV

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.