Background <p>Low-level light therapy (LLLT) and light-emitting diode (LED) therapy have gained popularity in aesthetic dermatology for their effectiveness and convenience in treating skin aging through photobiomodulation (PBM). Recent advancements have led to the development of a new near-infrared (nNIR) LED device with a broader spectrum, aiming to enhance skin rejuvenation and hair growth. This study aims to clinically evaluate the efficacy of this nNIR device.</p> Methods <p>The study included two segments: skin rejuvenation and hair growth evaluation. For skin rejuvenation, 20 participants aged 45–59 used an nNIR LED facial mask for 30 minutes, five times a week over 12 weeks. Parameters such as wrinkle count, skin moisture, elasticity, and density were measured. For hair growth, 25 participants aged 20–55 applied the same device to the scalp daily for 20 weeks, assessing hair growth at 6, 13, and 20 weeks.</p> Results <p>Skin rejuvenation showed significant improvements, with wrinkles decreasing by up to 27.22% and skin texture, elasticity, moisture, and density also improving. Hair growth evaluation indicated a 1.33% increase in hair count by 20 weeks, with high participant satisfaction and no adverse reactions reported.</p> Conclusion <p>The nNIR LED device demonstrated clinical efficacy in skin rejuvenation and hair growth, highlighting the benefits of a broader spectral range in PBM. While further research with larger and more diverse populations is recommended, this nNIR LED device suggests significant potential for advancements in aesthetic treatments.</p> Level of Evidence III <p>This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors <a href="http://www.springer.com/00266">www.springer.com/00266</a>.</p>