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<p>Ureteroscopy (URS) is the most commonly used minimally invasive method for treating ureteral stones. Postoperative infection and sepsis are among the most frequent complications following URS. This study investigated the predictive power of renal pelvis urine density (RPUD) and perinephric fat stranding (PFS) on preoperative non-contrast computed tomography for predicting postoperative infectious complications after URS for obstructive ureteral stones. Data from patients who underwent URS for obstructive ureteral stones between January 2020 and December 2025 were examined. Patient groups with and without postoperative infection were compared. Postoperative infectious complications were defined as symptomatic presentations suggestive of urinary tract infection that fulfilled predefined systemic inflammatory response syndrome (SIRS) criteria. Independent predictors were investigated using multivariate logistic regression analysis. According to multivariate logistic regression analysis, mean stone density, PFS, and RPUD were found to be independent predictive factors for postoperative infection (OR: 0.998, 95% CI: 0.996–0.999, <i>p</i>&lt;0.001; OR: 3.416, 95% CI: 1.582–7.372, <i>p</i> = 0.002; and OR: 1.114, 95% CI: 1.054–1.176, <i>p</i>&lt;0.001, respectively). In an additional sensitivity analysis restricted to objectively documented infections, higher RPUD values and greater PFS severity remained significantly associated with postoperative infectious complications. High RPUD values and increased PFS severity on preoperative NCCT may help identify patients at increased risk of clinically meaningful postoperative infectious complications following URS for obstructive ureteral stones and may facilitate closer postoperative surveillance.</p>

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Predictive value of renal pelvis urine density and perinephric fat stranding for infectious complications after ureteroscopy in patients with obstructive ureteral stones

  • 期刊论文

  • 发表日期：

    2026年7月30日

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  • Çağrı Coşkun,
  • Ender Cem Bulut,
  • Nihat Karabacak,
  • İrem Aleyna Teke,
  • Bora Küpeli

摘要

Ureteroscopy (URS) is the most commonly used minimally invasive method for treating ureteral stones. Postoperative infection and sepsis are among the most frequent complications following URS. This study investigated the predictive power of renal pelvis urine density (RPUD) and perinephric fat stranding (PFS) on preoperative non-contrast computed tomography for predicting postoperative infectious complications after URS for obstructive ureteral stones. Data from patients who underwent URS for obstructive ureteral stones between January 2020 and December 2025 were examined. Patient groups with and without postoperative infection were compared. Postoperative infectious complications were defined as symptomatic presentations suggestive of urinary tract infection that fulfilled predefined systemic inflammatory response syndrome (SIRS) criteria. Independent predictors were investigated using multivariate logistic regression analysis. According to multivariate logistic regression analysis, mean stone density, PFS, and RPUD were found to be independent predictive factors for postoperative infection (OR: 0.998, 95% CI: 0.996–0.999, p<0.001; OR: 3.416, 95% CI: 1.582–7.372, p = 0.002; and OR: 1.114, 95% CI: 1.054–1.176, p<0.001, respectively). In an additional sensitivity analysis restricted to objectively documented infections, higher RPUD values and greater PFS severity remained significantly associated with postoperative infectious complications. High RPUD values and increased PFS severity on preoperative NCCT may help identify patients at increased risk of clinically meaningful postoperative infectious complications following URS for obstructive ureteral stones and may facilitate closer postoperative surveillance.