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Background <p>Globally, the number of individuals identifying as transgender and gender-diverse [TGD] has grown in the last decade. This study aimed to perform a Danish linguistic translation and cultural adaptation of the GENDER-Q, a new patient-reported outcome measure [PROM] designed to evaluate outcomes of gender-affirming care.</p> Methods <p>The field test version of the GENDER-Q (959 items) was translated into Danish using guidelines from the International Society of Pharmacoeconomics and Outcomes Research and the World Health Organization to ensure accuracy, cultural relevance, and validity. This included two forward translations, a backward translation, an expert panel meeting, and two rounds of patient cognitive interviews.</p> Results <p>The forward translations resulted in revisions of 142 items, which were then harmonized to form the backward translation version. A comparison of the back translation to the original questionnaire led to a total of 43 changes to items and response options. The revised version was reviewed in an expert panel meeting and minor changes were made with 28 patient participants using cognitive debriefing interviews. The translated version was proofread, resulting in the Danish translation of the GENDER-Q.</p> Conclusions <p>The GENDER-Q was translated and culturally adapted for use in the Danish TGD adult population. The GENDER-Q has the potential to enhance the understanding and improvement of treatment and health-related quality-of-life outcomes for adults seeking gender-affirming care.</p> Level of Evidence: <p>Not gradable.</p>

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Danish translation and linguistic validation of the GENDER-Q, a patient-reported outcome measure for use in gender-affirming care

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年1月21日

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  • Michelle Mistry Igbokwe,
  • Lotte Poulsen,
  • Tine Taulbjerg Kristensen,
  • Anne F Klassen,
  • Manraj N Kaur,
  • Trisia Breitkopf,
  • Jack Graesser,
  • Rikke Holmgaard,
  • Jens Ahm Sørensen

摘要

Background

Globally, the number of individuals identifying as transgender and gender-diverse [TGD] has grown in the last decade. This study aimed to perform a Danish linguistic translation and cultural adaptation of the GENDER-Q, a new patient-reported outcome measure [PROM] designed to evaluate outcomes of gender-affirming care.

Methods

The field test version of the GENDER-Q (959 items) was translated into Danish using guidelines from the International Society of Pharmacoeconomics and Outcomes Research and the World Health Organization to ensure accuracy, cultural relevance, and validity. This included two forward translations, a backward translation, an expert panel meeting, and two rounds of patient cognitive interviews.

Results

The forward translations resulted in revisions of 142 items, which were then harmonized to form the backward translation version. A comparison of the back translation to the original questionnaire led to a total of 43 changes to items and response options. The revised version was reviewed in an expert panel meeting and minor changes were made with 28 patient participants using cognitive debriefing interviews. The translated version was proofread, resulting in the Danish translation of the GENDER-Q.

Conclusions

The GENDER-Q was translated and culturally adapted for use in the Danish TGD adult population. The GENDER-Q has the potential to enhance the understanding and improvement of treatment and health-related quality-of-life outcomes for adults seeking gender-affirming care.

Level of Evidence:

Not gradable.