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Introduction <p>Parenchymal haematoma (PH) is a potentially serious complication post endovascular treatment (EVT) and is associated with poor functional outcomes. It is unknown if modifiable factors can improve the outcomes of patients with PH. This study aimed to determine whether successful reperfusion is associated with favourable outcome in patients with ischemic stroke despite this complication.</p> Methods <p> In an international multi-centre study, favourable outcomes (mRS0-2) of patients achieving successful reperfusion (TICI 2b/3) were compared with outcomes of those with unsuccessful reperfusion.</p> Results <p> 346 patients were included in the final analysis. 36 patients had unsuccessful reperfusion (10.4%) while 310 had successful reperfusion (89.6%). Amongst patients with PH post-EVT, successful reperfusion conferred better 3-month favourable outcomes (20.32% vs 5.56%; p=0.032) and lower mortality rates (40.32% vs 72.22%; p &lt;0.001) compared with patients who had unsuccessful reperfusion.</p> Conclusion <p> Successful reperfusion remains a strong predictor of favourable outcome and reduced mortality in ischemic stroke patients with parenchymal haematoma post endovascular treatment.</p>

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Success reperfusion remains a strong predictor of favourable outcome and reduced mortality in ischemic stroke patients with parenchymal haematoma post endovascular treatment: an international multi-centre cohort study

  • 期刊论文

  • 发表日期：

    2026年1月22日

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  • Yimin Chen,
  • Keng Siang Lee,
  • Isabel Siow,
  • Yibei Dai,
  • Xiao Xiao,
  • Apar Garg,
  • Anil Gopinathan,
  • Cunli Yang,
  • Benjamin YQ Tan,
  • Mingxue Jing,
  • May Zin,
  • Hock Luen Teoh,
  • Ching-Hui Sia,
  • Mingzhu Feng,
  • Jicai Ma,
  • Lue Chen,
  • Sijie Zhou,
  • Zunbao Xu,
  • Yongting Zhou,
  • Yuzheng Lai,
  • Wenhong Peng,
  • Yihua He,
  • Mohammad Mofatteh,
  • Thanh N. Nguyen,
  • Suyue Pan,
  • Leonard Yeo

摘要

Introduction

Parenchymal haematoma (PH) is a potentially serious complication post endovascular treatment (EVT) and is associated with poor functional outcomes. It is unknown if modifiable factors can improve the outcomes of patients with PH. This study aimed to determine whether successful reperfusion is associated with favourable outcome in patients with ischemic stroke despite this complication.

Methods

In an international multi-centre study, favourable outcomes (mRS0-2) of patients achieving successful reperfusion (TICI 2b/3) were compared with outcomes of those with unsuccessful reperfusion.

Results

346 patients were included in the final analysis. 36 patients had unsuccessful reperfusion (10.4%) while 310 had successful reperfusion (89.6%). Amongst patients with PH post-EVT, successful reperfusion conferred better 3-month favourable outcomes (20.32% vs 5.56%; p=0.032) and lower mortality rates (40.32% vs 72.22%; p <0.001) compared with patients who had unsuccessful reperfusion.

Conclusion

Successful reperfusion remains a strong predictor of favourable outcome and reduced mortality in ischemic stroke patients with parenchymal haematoma post endovascular treatment.