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<p>Melanin is a dark colored pigment produced by various living organisms. In this study, the melanin-producing fungus was isolated from a washing machine and identified as <i>Scolecobasidium musae</i> by 18&#xa0;S rDNA analysis. Melanin production by <i>S. musae</i> was reported for the first time. Melanin was obtained from the dark-colored biomass produced by <i>S. musae</i> in submerged culture. The pigment was then purified, characterized, and identified. It was determined that purified melanin was dissolved easily in alkaline solutions but insoluble in organic solvents. Devices such as UV-Vis spectroscopy, XRD, FTIR, NMR, EPR, and elemental analysis were used to determine the chemical content and structure of the produced melanin. The melanin synthesis pathway was investigated using melanin inhibitors and by performing LC-MS analysis of the fermentation medium in which <i>S. musae</i> grew. It was found that the newly produced melanin from <i>S. musae</i> possesses antioxidant and photoprotective properties (sun protection and UV protection for <i>Staphylococcus aureus</i>). These results provide new possibilities for the biotechnological applications of this naturally producing melanin pigment.</p> Graphical Abstract <p></p>

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Characterization of melanin from the fungus Scolecobasidium Musae and its antioxidant and photoprotective properties

  • 期刊论文

  • 发表日期：

    2025年3月6日

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  • Fatma Meryem Bozhuyuk,
  • Murat Ozdal

摘要

Melanin is a dark colored pigment produced by various living organisms. In this study, the melanin-producing fungus was isolated from a washing machine and identified as Scolecobasidium musae by 18 S rDNA analysis. Melanin production by S. musae was reported for the first time. Melanin was obtained from the dark-colored biomass produced by S. musae in submerged culture. The pigment was then purified, characterized, and identified. It was determined that purified melanin was dissolved easily in alkaline solutions but insoluble in organic solvents. Devices such as UV-Vis spectroscopy, XRD, FTIR, NMR, EPR, and elemental analysis were used to determine the chemical content and structure of the produced melanin. The melanin synthesis pathway was investigated using melanin inhibitors and by performing LC-MS analysis of the fermentation medium in which S. musae grew. It was found that the newly produced melanin from S. musae possesses antioxidant and photoprotective properties (sun protection and UV protection for Staphylococcus aureus). These results provide new possibilities for the biotechnological applications of this naturally producing melanin pigment.

Graphical Abstract