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<p>Drug-induced osteoporosis (DIO) is an important part of secondary osteoporosis. This article discusses the effects of common drugs on bone metabolism and the possible mechanisms leading to osteoporosis and discusses the possible treatment strategies. Although anti-osteoporosis drugs can effectively improve bone mineral density and reduce the risk of fracture and prevent the occurrence of DIO, long-term use of anti-osteoporosis drugs may lead to skeletal adverse events such as atypical femur fracture. Therefore, for the prevention and treatment of DIO, the benefits and adverse reactions of drugs should be comprehensively considered to develop an individualized treatment plan for patients.</p>

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Research progress of drug-induced osteoporosis

  • 期刊论文

  • 发表日期：

    2026年3月16日

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  • Wenbin Tan,
  • Ting He,
  • Jia Li

摘要

Drug-induced osteoporosis (DIO) is an important part of secondary osteoporosis. This article discusses the effects of common drugs on bone metabolism and the possible mechanisms leading to osteoporosis and discusses the possible treatment strategies. Although anti-osteoporosis drugs can effectively improve bone mineral density and reduce the risk of fracture and prevent the occurrence of DIO, long-term use of anti-osteoporosis drugs may lead to skeletal adverse events such as atypical femur fracture. Therefore, for the prevention and treatment of DIO, the benefits and adverse reactions of drugs should be comprehensively considered to develop an individualized treatment plan for patients.