Introduction and Hypothesis <p>This study is aimed at comparing home with hospital removal of urinary catheters after surgical correction of pelvic floor disorders.</p> Methods <p>This is a retrospective cohort study at a single urogynecology practice (1 May 2020 to 30 November 2024). A total of 184 patients, age 33–86&#xa0;years (mean 66.2) with a diagnosis of pelvic floor disorder underwent home removal (primary <i>n</i> = 31, secondary <i>n</i> = 34) or hospital removal (<i>n</i> = 153) of a urinary catheter after pelvic floor reconstructive surgery (IRB Pro2024-0473).</p> Results <p>The incidence of urinary retention was significantly lower in the primary home-removal group (3.3% ± 3.3%, <i>n</i> = 1, 95% CI 0–9.8%) compared with the hospital-removal group (27.5% ± 3.6%, <i>n</i> = 42, 95% CI 20.3–34.6%; <i>p</i> = 0.004). Of those with urinary retention, most underwent home removal for a secondary void trial (<i>n</i> = 34, 81.0%). The incidence of catheter-associated urinary tract infections (CAUTIs) was increased but not statistically significantly in the primary home-removal group (22.6% ± 7.6%, 95% CI 7.0–38.2%) compared with the hospital-removal group (9.2% ± 2.3%, 95% CI 4.5–13.8%; <i>p</i> = 0.056). The duration of the primary hospital admission was significantly shorter for the home removal of urinary catheterization (0.3 ± 0.1 day vs 1.1 ± 0.1 day; <i>p</i> &lt; 0.0001). There was no significant difference in readmission (<i>p</i> = 0.593) or return to the operating room (<i>p</i> &gt; 0.999).</p> Conclusions <p>Home catheter removal after pelvic floor reconstructive surgery appears feasible in selected patients and is associated with reduced hospital utilization and lower urinary retention rates. However, a trend toward increased CAUTIs cannot be dismissed. Therefore, prospective randomized trials are needed to definitively establish safety and identify appropriate patient selection criteria before widespread adoption.</p>