<p>This research integrates deep learning, copula functions, and survival analysis to effectively handle highly correlated and right-censored multivariate survival data. It introduces copula-based activation functions (Clayton, Gumbel, and their combinations) to model the nonlinear dependencies inherent in such data. Through simulation studies and analysis of real breast cancer data, our proposed CNN-LSTM with copula-based activation functions for multivariate multi-types of survival responses enhances prediction accuracy by explicitly addressing right-censored data and capturing complex patterns. The model’s performance is evaluated using Shewhart control charts, focusing on the average run length (ARL).</p>

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Deep learning-based survival analysis with copula-based activation functions for multivariate response prediction

  • Jong-Min Kim,
  • Il Do Ha,
  • Sangjin Kim

摘要

This research integrates deep learning, copula functions, and survival analysis to effectively handle highly correlated and right-censored multivariate survival data. It introduces copula-based activation functions (Clayton, Gumbel, and their combinations) to model the nonlinear dependencies inherent in such data. Through simulation studies and analysis of real breast cancer data, our proposed CNN-LSTM with copula-based activation functions for multivariate multi-types of survival responses enhances prediction accuracy by explicitly addressing right-censored data and capturing complex patterns. The model’s performance is evaluated using Shewhart control charts, focusing on the average run length (ARL).