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Purpose <p>A long-term evaluation of <i>The Caregiver Pathway</i>, a model to follow up family caregivers on Post-intensive Care Symptoms among Family (PICS-F).</p> Methods <p>A single-center non-blinded randomized controlled trial including 196 family caregivers to critically ill patients randomized to intervention (<i>n</i> = 101) or control group (<i>n</i> = 95). <i>The Caregiver Pathway</i> intervention consists of: (1) a digital assessment followed by a conversation with a nurse in the first days at the ICU, (2) a supportive card when leaving the ICU, (3) an offer to receive a phone call following patient transfer to a step-down unit, and (4) a follow-up conversation within 3&#xa0;months after discharge. Outcome measures were collected at 6 and 12&#xa0;months, including symptoms of post-traumatic stress disorder (PTSD), anxiety, depression, Health-related Quality of Life (HRQoL), hope, and self-efficacy.</p> Results <p><i>The Caregiver Pathway</i> was associated with a significant effect for symptoms of PTSD after 6&#xa0;months compared with controls, mean IES-R score: 25.8 [95% CI 21.9–29.7] versus 30.9 [95% CI 26.7–35.0], <i>p</i> = 0.009, and a trend toward an effect after 12&#xa0;months: IES-R score: 25.0 [95% CI 21.3–28.7] versus 28.4 [95% CI 24.1–32.7], <i>p</i> = 0.057. Subgroup analyses at 12&#xa0;months showed a significant intervention effect among family caregivers of patients who survived compared to controls for PTSD, IES-R score: 19.8 [95% CI 15.3–24.2] versus 29.1 [95% CI 23.5–34.6], <i>p</i> = 0.001, and anxiety, HADS-A score: 4.3 [95% CI 3.1–5.4] versus 6.8 [95% CI 5.2–8.4], <i>p</i> = 0.003.</p> Conclusions <p><i>The Caregiver Pathway</i> has the potential to reduce the symptoms of PICS-F, especially among family caregivers whose patient has survived.</p>

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Effects of The Caregiver Pathway intervention on symptoms of post-intensive care syndrome among family caregivers to critically ill patients: long-term results from a randomized controlled trial

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年10月6日

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  • Solbjørg Watland,
  • Lise Solberg Nes,
  • Øivind Ekeberg,
  • Morten Rostrup,
  • Elizabeth Hanson,
  • Mirjam Ekstedt,
  • Milada Hagen,
  • Elin Børøsund

摘要

Purpose

A long-term evaluation of The Caregiver Pathway, a model to follow up family caregivers on Post-intensive Care Symptoms among Family (PICS-F).

Methods

A single-center non-blinded randomized controlled trial including 196 family caregivers to critically ill patients randomized to intervention (n = 101) or control group (n = 95). The Caregiver Pathway intervention consists of: (1) a digital assessment followed by a conversation with a nurse in the first days at the ICU, (2) a supportive card when leaving the ICU, (3) an offer to receive a phone call following patient transfer to a step-down unit, and (4) a follow-up conversation within 3 months after discharge. Outcome measures were collected at 6 and 12 months, including symptoms of post-traumatic stress disorder (PTSD), anxiety, depression, Health-related Quality of Life (HRQoL), hope, and self-efficacy.

Results

The Caregiver Pathway was associated with a significant effect for symptoms of PTSD after 6 months compared with controls, mean IES-R score: 25.8 [95% CI 21.9–29.7] versus 30.9 [95% CI 26.7–35.0], p = 0.009, and a trend toward an effect after 12 months: IES-R score: 25.0 [95% CI 21.3–28.7] versus 28.4 [95% CI 24.1–32.7], p = 0.057. Subgroup analyses at 12 months showed a significant intervention effect among family caregivers of patients who survived compared to controls for PTSD, IES-R score: 19.8 [95% CI 15.3–24.2] versus 29.1 [95% CI 23.5–34.6], p = 0.001, and anxiety, HADS-A score: 4.3 [95% CI 3.1–5.4] versus 6.8 [95% CI 5.2–8.4], p = 0.003.

Conclusions

The Caregiver Pathway has the potential to reduce the symptoms of PICS-F, especially among family caregivers whose patient has survived.