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<p>In pre-eclampsia (PE), vasoconstriction of peripheral resistance vessels is particularly prevalent and may be specifically observed in the Doppler pattern of the ophthalmic artery (OA). This observation is based on the concept of pulse wave (PW) propagation and reflection. As a&#xa0;result of PW propagation in the systemic circulation, with reflection and kranial transmission, the OA shows a&#xa0;second systolic peak P2 in addition to the primary systolic peak, P1. Mainly in PE, the peak ratio PR = P2/P1 is increased and serves as a&#xa0;Doppler index for the OA. The normal value is PR = 0.54 ± 0.097 (mean ± standard deviation) and remains constant between 20&#xa0;and 40&#xa0;weeks’ gestation. The cut-off for the complementary PE diagnosis is PR = 0.75. Numerous studies have shown that OA Doppler analysis is important in the prediction and diagnosis of PE. In the future, it is expected that the OA Doppler will be integrated into PE risk assessment.</p>

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Arteria ophthalmica und Präeklampsie

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年6月17日

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  • Markus Gonser,
  • Ladina Vonzun

摘要

In pre-eclampsia (PE), vasoconstriction of peripheral resistance vessels is particularly prevalent and may be specifically observed in the Doppler pattern of the ophthalmic artery (OA). This observation is based on the concept of pulse wave (PW) propagation and reflection. As a result of PW propagation in the systemic circulation, with reflection and kranial transmission, the OA shows a second systolic peak P2 in addition to the primary systolic peak, P1. Mainly in PE, the peak ratio PR = P2/P1 is increased and serves as a Doppler index for the OA. The normal value is PR = 0.54 ± 0.097 (mean ± standard deviation) and remains constant between 20 and 40 weeks’ gestation. The cut-off for the complementary PE diagnosis is PR = 0.75. Numerous studies have shown that OA Doppler analysis is important in the prediction and diagnosis of PE. In the future, it is expected that the OA Doppler will be integrated into PE risk assessment.