<p>This case report describes a&#xa0;rare case of testicular metastasis from renal cell carcinoma, which led to first diagnosis of the primary. The patient presented with a&#xa0;progressive painless swelling of the left testicle. After initial suspicion of a&#xa0;testicular tumor, inguinal excision of the testis was performed, which confirmed the presence of a&#xa0;clear cell carcinoma. Further investigations revealed evidence of a&#xa0;primary carcinoma on the left-lower pole of the kidney, which was removed by partial nephrectomy. Histopathologically, clear cell renal cell carcinoma was confirmed. Treatment was supplemented by adjuvant immunotherapy with pembrolizumab. Postoperative follow-up has shown no evidence of recurrence to date.</p>

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Erstdiagnose eines Nierenzellkarzinoms über eine Hodenmetastase

  • Leonhard Buck,
  • Hans Christoph von Knobloch,
  • Jakob Kohler,
  • Fatih Yalcin,
  • Christiane Maria Stuhlmann-Laeisz,
  • Severin Rodler,
  • Jonas Jarczyk,
  • Philipp Nuhn

摘要

This case report describes a rare case of testicular metastasis from renal cell carcinoma, which led to first diagnosis of the primary. The patient presented with a progressive painless swelling of the left testicle. After initial suspicion of a testicular tumor, inguinal excision of the testis was performed, which confirmed the presence of a clear cell carcinoma. Further investigations revealed evidence of a primary carcinoma on the left-lower pole of the kidney, which was removed by partial nephrectomy. Histopathologically, clear cell renal cell carcinoma was confirmed. Treatment was supplemented by adjuvant immunotherapy with pembrolizumab. Postoperative follow-up has shown no evidence of recurrence to date.