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Clinical/methodological issue <p>Pediatric sarcomas representing a&#xa0;rare, heterogenous group of highly malignant tumors. Due to their aggressiveness and complex anatomy during growth, precise imaging is essential for prognosis.</p> Standard radiologic methods <p>Magnetic resonance imaging (MRI), using specific pediatric protocols (small field of view [FOV], thin slices), is the gold standard for local staging. Ultrasound is pivotal for primary diagnosis and biopsy planning, while low-dose chest computed tomography (CT) is used to assess pulmonary metastases.</p> Methodological innovations <p>Diffusion-weighted MRI and positron-emission tomography (PET)/MRI represents a&#xa0;low-radiation and highly efficient alternative to PET/CT for whole-body staging, especially for long-term aftercare.</p> Performance <p>Imaging enables precise delineation of neurovascular structures and growth plates, forming the basis for limb-sparing surgical procedures. However, differentiating between vital residual tumor, recurrence, and posttherapeutic changes (scars, edema) remains challenging.</p> Achievements <p>The consistent application of standardized study protocols and the interdisciplinary integration of radiology, oncology, and surgery are crucial for the success of modern therapeutic concepts.</p>

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Sarkome im Kindesalter

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年2月10日

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  • Ilias Tsiflikas

摘要

Clinical/methodological issue

Pediatric sarcomas representing a rare, heterogenous group of highly malignant tumors. Due to their aggressiveness and complex anatomy during growth, precise imaging is essential for prognosis.

Standard radiologic methods

Magnetic resonance imaging (MRI), using specific pediatric protocols (small field of view [FOV], thin slices), is the gold standard for local staging. Ultrasound is pivotal for primary diagnosis and biopsy planning, while low-dose chest computed tomography (CT) is used to assess pulmonary metastases.

Methodological innovations

Diffusion-weighted MRI and positron-emission tomography (PET)/MRI represents a low-radiation and highly efficient alternative to PET/CT for whole-body staging, especially for long-term aftercare.

Performance

Imaging enables precise delineation of neurovascular structures and growth plates, forming the basis for limb-sparing surgical procedures. However, differentiating between vital residual tumor, recurrence, and posttherapeutic changes (scars, edema) remains challenging.

Achievements

The consistent application of standardized study protocols and the interdisciplinary integration of radiology, oncology, and surgery are crucial for the success of modern therapeutic concepts.