Scholarlink

Clinical/methodical issue <p>Allergic bronchopulmonary aspergillosis (ABPA) is a&#xa0;rare but potentially severe hypersensitivity reaction to <i>Aspergillus fumigatus</i>, primarily affecting patients with asthma or cystic fibrosis. Early diagnosis is crucial to prevent irreversible lung damage.</p> Standard radiological methods <p>High-resolution computed tomography (HRCT) is the standard imaging method for detecting bronchiectasis and other typical findings. Common features include central, saccular bronchiectasis, mucus impaction, and centrilobular micronodules. Radiological assessment must be closely integrated with clinical and laboratory parameters.</p> Methodical innovations <p>The revised 2024 International Society for Human and Animal Mycology (ISHAM) criteria further emphasize the diagnostic importance of radiological features. High-attenuation mucus (HAM) is considered a&#xa0;highly specific finding and may confirm the diagnosis. Modern classification systems allow more precise disease staging.</p> Performance <p>HRCT provides extremely high sensitivity for the radiological hallmarks of ABPA. Detection of HAM is regarded as nearly pathognomonic. Fleeting infiltrates and reversible changes are reliably visualized. Correlating radiological findings with laboratory parameters significantly improves diagnostic accuracy.</p> Achievements <p>HRCT remains the indispensable imaging modality for diagnosing and monitoring ABPA.</p> Practical recommendations <p>In cases of clinical suspicion, early HRCT of the thorax should be performed. A combination of radiological findings and serological criteria is recommended to confirm the diagnosis. HRCT can be used to detect reversible infiltrates and assess response to treatment.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Allergische bronchopulmonale Aspergillose – das muss die Radiologie wissen

  • 期刊论文

  • 发表日期：

    2026年2月3日

查看全文
  • Luca Salhöfer,
  • Matthias Welsner,
  • Hanna Lehmann,
  • Friederike-Charlotte Salhöfer,
  • Johannes Haubold,
  • Marcel Opitz

摘要

Clinical/methodical issue

Allergic bronchopulmonary aspergillosis (ABPA) is a rare but potentially severe hypersensitivity reaction to Aspergillus fumigatus, primarily affecting patients with asthma or cystic fibrosis. Early diagnosis is crucial to prevent irreversible lung damage.

Standard radiological methods

High-resolution computed tomography (HRCT) is the standard imaging method for detecting bronchiectasis and other typical findings. Common features include central, saccular bronchiectasis, mucus impaction, and centrilobular micronodules. Radiological assessment must be closely integrated with clinical and laboratory parameters.

Methodical innovations

The revised 2024 International Society for Human and Animal Mycology (ISHAM) criteria further emphasize the diagnostic importance of radiological features. High-attenuation mucus (HAM) is considered a highly specific finding and may confirm the diagnosis. Modern classification systems allow more precise disease staging.

Performance

HRCT provides extremely high sensitivity for the radiological hallmarks of ABPA. Detection of HAM is regarded as nearly pathognomonic. Fleeting infiltrates and reversible changes are reliably visualized. Correlating radiological findings with laboratory parameters significantly improves diagnostic accuracy.

Achievements

HRCT remains the indispensable imaging modality for diagnosing and monitoring ABPA.

Practical recommendations

In cases of clinical suspicion, early HRCT of the thorax should be performed. A combination of radiological findings and serological criteria is recommended to confirm the diagnosis. HRCT can be used to detect reversible infiltrates and assess response to treatment.