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<p>Alzheimer’s disease is one of the most common causes of dementia in older adults. Since 2024, monoclonal antibody therapy has been available, which can slow disease progression at certain stages. During therapy, magnetic resonance imaging changes called amyloid-related imaging abnormalities (ARIA)—edema (ARIA-E) and hemorrhage (ARIA-H)—must be monitored at specific points during treatment; depending on severity, therapy may need to be paused. Cerebral amyloid angiopathy (CAA) and its inflammatory form (CAA-I) should be considered in the differential diagnosis.</p>

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Neue Therapieansätze bei Morbus Alzheimer

  • 期刊论文

  • 发表日期：

    2026年1月29日

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  • Alena Haußmann

摘要

Alzheimer’s disease is one of the most common causes of dementia in older adults. Since 2024, monoclonal antibody therapy has been available, which can slow disease progression at certain stages. During therapy, magnetic resonance imaging changes called amyloid-related imaging abnormalities (ARIA)—edema (ARIA-E) and hemorrhage (ARIA-H)—must be monitored at specific points during treatment; depending on severity, therapy may need to be paused. Cerebral amyloid angiopathy (CAA) and its inflammatory form (CAA-I) should be considered in the differential diagnosis.