Sichere Arzneimittelanwendung bei Kindern
摘要
Drug administration in children is complex and prone to errors due to the lack of age-appropriate pediatric formulations and the need to adjust dosages on an individual basis. Although liquid oral medications enable flexible dosing and better acceptance, they are associated with numerous administration problems. In the case of dry syrups, errors in the reconstitution, such as insufficient shaking, incorrect amounts of water, or the use of hot water, often lead to incorrect concentrations of active ingredients. Suspensions must be shaken before each withdrawal, as otherwise sedimentation leads to systematic underdosing and overdosing. Dosing aids such as measuring spoons also harbor high inaccuracies and dosing syringes are much more reliable. With droppers, care must be taken to maintain the correct angle of inclination when removing the dropper from the respective preparation as deviations from the required angle lead to considerable dosage fluctuations. In addition to long-term medication, emergency medicines play a central role in pediatrics, for example in the case of epileptic seizures or anaphylactic reactions. Their often counterintuitive use leads to high error rates in studies when used by parents and caregivers. Training with demonstration models reduces errors in use, increases the confidence of users and their willingness to administer the medication and also promotes the social participation of affected children. Supplementary measures such as clear written agreements and guidelines further increase confidence in medical emergency situations. Overall, targeted education and training are essential for reducing medication errors and improving the quality of care.